Remarkable progress has been achieved in understanding the regulation of gene
expression and protein translation, and how aberrancies in these template-driven processes …

Heparan sulfate (HS) is a structurally complex polysaccharide located on the cell surface
and in the extracellular matrix, where it participates in numerous biological processes …

There is an emerging interest in the extracellular matrix (ECM) of the lung, especially in the
role it plays in development and disease. There is a rapid change from the classical view of …

Heparan sulfate (HS) is a complex linear polysaccharide that modulates a wide range of
biological functions. Elucidating the structure–function relationship of HS has been …

An important hallmark of tissue remodeling is the dynamic turnover of extracellular matrix
(ECM). ECM performs a variety of functions in tissue repair including scaffold formation …

Heparan sulfate proteoglycans (HSPGs) are integral components of the lung. Changes in
HSPGs have been documented in idiopathic pulmonary fibrosis (IPF). Many of the biological …

What can we learn from embryogenesis to increase our understanding of how regeneration
of damaged adult lung tissue could be induced in serious lung diseases such as chronic …

The lung epithelial glycocalyx is a carbohydrate-enriched layer lining the pulmonary
epithelial surface. Although epithelial glycocalyx visualization has been reported, its …

Hyaluronan (HA) has diverse functions in normal lung homeostasis and pulmonary disease.
HA constitutes the major glycosaminoglycan in lung tissue, with HA degradation products …

Hyaluronan (HA) is a polymer of molecular mass from 2 105 to 10 106 comprising repeating
disaccharide units of glucuronic acid and N-acetyl-D-glucosamine. HA is abundant, present …