The Effects of Chronic Early-life Social Isolation on Hippocampal Cell Number and Hippocampal-Dependent Learning and Memory in Male and Female Rats

N D'Costa - 2019 - uwspace.uwaterloo.ca
Before, and for a considerable time after birth, the brain is especially plastic and vulnerable
to influences from the environment. Exposure to stressful, or adverse, early-life social …

Chronic early-life social isolation enhances spatial memory in male and female rats

S Davari, N D'Costa, R Ramezan, JG Mielke - Behavioural Brain Research, 2023 - Elsevier
Social adversity during childhood and adolescence can alter brain development in ways that
may increase the likelihood of many prominent mental illnesses. To determine the …

Does psychosocial stress experienced at different points across the rat lifespan cause sex-specific changes in spatial learning and memory and plasticity-related …

S Davari Dowlatabadi - 2023 - uwspace.uwaterloo.ca
Overview Considering that susceptibility to a range of diseases appears strongly influenced
by both sex and exposure to social stress, there is a need to evaluate how adverse …

[HTML][HTML] Age-related impact of social isolation in mice: Young vs middle-aged

DM Magalhães, M Mampay, AM Sebastião… - Neurochemistry …, 2024 - Elsevier
Social isolation is a chronic mild stressor and a significant risk factor for mental health
disorders. Herein we explored the impact of social isolation on depression-and anxiety-like …

[HTML][HTML] Social isolation-induced transcriptomic changes in mouse hippocampus impact the synapse and show convergence with human genetic risk for …

A Laighneach, JP Kelly, L Desbonnet, L Holleran… - Plos one, 2023 - journals.plos.org
Early life stress (ELS) can impact brain development and is a risk factor for
neurodevelopmental disorders such as schizophrenia. Post-weaning social isolation (SI) is …

Enduring effects induced by brief and repeated periods of social isolation stress during early adolescence

GF Mancini, E Marchetta, M Splendori… - Abstract book, 2019 - iris.uniroma1.it
Introduction: Social isolation stress (SIS) is one of the most commonly used stress paradigm
to reproduce psychiatric-like disorders in rodents and it is generally conducted from weaning …

[PDF][PDF] The effect of social isolation rearing on the development of the hippocampus and serotonergic function

S Muchimapura, CA Marsden - Thai J Physiol Sci, 2004 - Citeseer
Rearing rats in social isolation from weaning results in long-term effects on brain structure,
neurotransmitter function and behavior and many of the effects mimic those seen in …

Enduring behavioral effects of brief and repeated periods of social isolation stress during early adolescence

GF Mancini, E Marchetta, M Splendori… - Abstract Book, 2019 - iris.uniroma1.it
Social isolation stress (SIS) is one of the most commonly used stress paradigm to reproduce
psychiatric-like disorders in rodents and it is generally conducted from weaning to …

Chronic social isolation decreases glutamate and glutamine levels and induces oxidative stress in the rat hippocampus

Y Shao, G Yan, Y Xuan, H Peng, QJ Huang… - Behavioural brain …, 2015 - Elsevier
Social isolation (SI) rearing of rodents is a developmental manipulation, which is commonly
compared with the psychological stressors in humans as it produces several behavioral …

Subregional expression of hippocampal glutamatergic and GABAergic genes in F344 rats with social isolation after weaning

H Iwata, Y Yamamuro - Comparative medicine, 2016 - ingentaconnect.com
Many studies have shown that postweaning social isolation (pwSI) alters various behavioral
phenotypes, including hippocampusdependent tasks. Here, we report the comprehensive …