Diagnostic biomarkers for obsessive-compulsive disorder: A reasonable quest or ignis fatuus?
Obsessive-compulsive disorder (OCD) has been associated with a wide range of biological
and neurocognitive findings, which could assist in the search for biomarkers. We conducted …
and neurocognitive findings, which could assist in the search for biomarkers. We conducted …
A trans-diagnostic perspective on obsessive-compulsive disorder
CM Gillan, NA Fineberg, TW Robbins - Psychological medicine, 2017 - cambridge.org
Progress in understanding the underlying neurobiology of obsessive-compulsive disorder
(OCD) has stalled in part because of the considerable problem of heterogeneity within this …
(OCD) has stalled in part because of the considerable problem of heterogeneity within this …
Can neuroimaging provide reliable biomarkers for obsessive-compulsive disorder? A narrative review
I Frydman, JB de Salles Andrade, P Vigne… - Current psychiatry …, 2016 - Springer
In this integrative review, we discuss findings supporting the use neuroimaging biomarkers
in the diagnosis and treatment of obsessive-compulsive disorder (OCD). To do so, we have …
in the diagnosis and treatment of obsessive-compulsive disorder (OCD). To do so, we have …
What is the optimal way to subdivide obsessive-compulsive disorder?
The clinical presentation of obsessive-compulsive disorder (OCD) varies not only across
patients but over the course of the disorder. This diversity indicates that OCD is a …
patients but over the course of the disorder. This diversity indicates that OCD is a …
Neuropsychological investigations in obsessive–compulsive disorder: A systematic review of methodological challenges
A Abramovitch, A Mittelman, AP Tankersley… - Psychiatry …, 2015 - Elsevier
The inconsistent nature of the neuropsychology literature pertaining to obsessive–
compulsive disorder (OCD) has long been recognized. However, individual studies …
compulsive disorder (OCD) has long been recognized. However, individual studies …
Assessment of obsessive–compulsive disorder: review and future directions
Careful evaluation of obsessive–compulsive disorder (OCD) is critical owing to its under-
recognition, difficulty ascertaining accurate diagnoses and the need for detailed treatment …
recognition, difficulty ascertaining accurate diagnoses and the need for detailed treatment …
Does work on obsessive–compulsive spectrum disorders contribute to understanding the heterogeneity of obsessive–compulsive disorder?
BACKGROUND: There is a growing literature on the concept of an obsessive–compulsive
spectrum of disorders. Here, we consider the different dimensions on which obsessive …
spectrum of disorders. Here, we consider the different dimensions on which obsessive …
Deep clinical phenotyping of patients with obsessive-compulsive disorder: an approach towards detection of organic causes and first results
In the revised diagnostic classification systems ICD-11 and DSM-5, secondary, organic
forms of obsessive-compulsive disorder (OCD) are implemented as specific nosological …
forms of obsessive-compulsive disorder (OCD) are implemented as specific nosological …
Endophenotypes of obsessive–compulsive disorder: Current status and future directions
S Taylor - Journal of Obsessive-Compulsive and Related …, 2012 - Elsevier
Twin research shows that obsessive–compulsive disorder (OCD) arises from a combination
of genetic and environmental factors, including those that are general (OCD nonspecific) …
of genetic and environmental factors, including those that are general (OCD nonspecific) …
Toward identifying reproducible brain signatures of obsessive-compulsive profiles: rationale and methods for a new global initiative
HB Simpson, OA Van Den Heuvel, EC Miguel… - BMC psychiatry, 2020 - Springer
Background Obsessive-compulsive disorder (OCD) has a lifetime prevalence of 2–3% and
is a leading cause of global disability. Brain circuit abnormalities in individuals with OCD …
is a leading cause of global disability. Brain circuit abnormalities in individuals with OCD …