Oxytocin receptor gene DNA methylation: a biomarker of treatment response in obsessive-compulsive disorder?
MA Schiele, C Thiel, L Kollert, L Fürst… - Psychotherapy and …, 2020 - karger.com
Introduction: Obsessive-compulsive disorder (OCD) is associated with high chronicity and
treatment resistance, indicating the need for early therapy response markers enabling fast …
treatment resistance, indicating the need for early therapy response markers enabling fast …
Hypermethylation of the oxytocin receptor gene (OXTR) in obsessive-compulsive disorder: Further evidence for a biomarker of disease and treatment response
Obsessive-compulsive disorder (OCD) has recently been linked to increased methylation
levels in the oxytocin receptor (OXTR) gene, and OXTR hypermethylation has predicted a …
levels in the oxytocin receptor (OXTR) gene, and OXTR hypermethylation has predicted a …
Reduced DNA methylation of the oxytocin receptor gene is associated with obsessive-compulsive disorder
Background Oxytocin is an important neuromodulator involved in cognition and socio-
emotional processing that exerts its central activities via oxytocin receptors. Epigenetic …
emotional processing that exerts its central activities via oxytocin receptors. Epigenetic …
Epigenetic evidence for involvement of the oxytocin receptor gene in obsessive–compulsive disorder
Background Obsessive–compulsive disorder (OCD) is a chronic neurodevelopmental
disorder that affects up to 3% of the general population. Although epigenetic mechanisms …
disorder that affects up to 3% of the general population. Although epigenetic mechanisms …
Oxytocin receptor gene methylation in male and female PTSD patients and trauma-exposed controls
L Nawijn, IM Krzyzewska, M Van Zuiden… - European …, 2019 - Elsevier
Oxytocin receptor gene (OXTR) DNA-methylation levels have been associated with trauma-
exposure, mood-and anxiety disorders, and social processes relevant to posttraumatic …
exposure, mood-and anxiety disorders, and social processes relevant to posttraumatic …
Oxytocin receptor gene polymorphisms exert a modulating effect on the onset age in patients with obsessive-compulsive disorder
JI Kang, HW Kim, CH Kim, EH Hwang… - Psychoneuroendocrinology, 2017 - Elsevier
The oxytocin receptor (OXTR) is a potential candidate in the pathophysiology of obsessive-
compulsive disorder (OCD). The present study investigated the association between …
compulsive disorder (OCD). The present study investigated the association between …
Methylation of the oxytocin receptor gene in clinically depressed patients compared to controls: The role of OXTR rs53576 genotype
I Reiner, MH Van IJzendoorn… - Journal of psychiatric …, 2015 - Elsevier
The emerging field of epigenetics provides a biological basis for gene-environment
interactions relevant to depression. We focus on DNA methylation of exon 1 and 2 of the …
interactions relevant to depression. We focus on DNA methylation of exon 1 and 2 of the …
DNA methylation of OXTR is associated with parasympathetic nervous system activity and amygdala morphology
K Lancaster, L Goldbeck, MH Puglia… - Social cognitive and …, 2018 - academic.oup.com
Oxytocin has anxiolytic properties whose mechanisms of action are still being identified.
DNA methylation in the promoter region of the oxytocin receptor gene (OXTR), an epigenetic …
DNA methylation in the promoter region of the oxytocin receptor gene (OXTR), an epigenetic …
Regulation of oxytocin receptor gene expression in obsessive–compulsive disorder: a possible role for the microbiota-host epigenetic axis
Background Obsessive–compulsive disorder (OCD) is a prevalent and severe clinical
condition. Robust evidence suggests a gene-environment interplay in its etiopathogenesis …
condition. Robust evidence suggests a gene-environment interplay in its etiopathogenesis …
Differential methylation of the oxytocin receptor gene in patients with anorexia nervosa: a pilot study
YR Kim, JH Kim, MJ Kim, J Treasure - PloS one, 2014 - journals.plos.org
Background and Aim Recent studies in patients with anorexia nervosa suggest that oxytocin
may be involved in the pathophysiology of anorexia nervosa. We examined whether there …
may be involved in the pathophysiology of anorexia nervosa. We examined whether there …