The role of N-acetylcysteine (NAC) in the treatment of acetaminophen induced acute liver
injury (ALI) is well established but its role in non-acetaminophen induced ALI is still elusive …

Aims N‐acetylcysteine (NAC) may be useful in the management of non‐paracetamol drug‐
induced liver injury (DILI). Our objective was to review systematically evidence for the use of …

Background The American Association for the Study of Liver Diseases recommends that N-
acetylcysteine (NAC) may be beneficial in non-acetaminophen-related drug-induced liver …

Results A total of 3 studies [2 randomized controlled trials (RCTs) and 1 non-randomized
cohort] were pooled in this meta-analysis. TFS was significantly higher in patients given …

Introduction: Idiosyncratic drug-induced liver injury (DILI) is a rare adverse reaction to drugs
and other xenobiotics. DILI has different grades of severity and may lead to acute liver failure …

Background Acute liver failure (ALF) is a rare but highly mortal condition without liver
transplantation (LT). N-acetylcysteine (NAC), a glutathione precursor that detoxifies the …

Background Drug-induced liver injury (DILI) refers to acute or chronic liver injury that may
occur as a consequence of using drugs and herbal or dietary supplements. Specific …

Aims: N-Acetylcysteine (NAC) is used as an antidote in acetaminophen (APAP) overdose to
prevent and mitigate drug-induced liver injury (DILI). Our objective was to systematically …

Results A total of 672 patients were included in this meta-analysis from 5 prospective studies
(NAC group: n= 334; control group: n= 338). Viral hepatitis (45.8% vs. 32.8%) followed by …

Abstract Introduction and Aim Previous studies and systematic reviews have not provided
conclusive evidence on the effect of N-acetylcysteine (NAC) in non-acetaminophen-induced …