Recently, necroptosis has emerged as one of the important mechanisms of ischemia stroke.
Necroptosis can be rapidly activated in endothelial cells to cause vascular damage and …

Necroptosis, a novel type of programmed cell death, is involved in stroke-induced ischemic
brain injury. Although studies have sought to explore the mechanisms of necroptosis, its …

Aim Brain microvascular endothelial cells (BMVECs), as the important structure of blood-
brain barrier (BBB), play a vital role in ischemic stroke. Pyroptosis of different cells in the …

Pyroptosis and necroptosis are closely associated with the mechanism underlying cerebral
ischemia‑reperfusion (I/R) injury. The combination of astragaloside IV (AST IV) and Panax …

Endothelium (EC) is a key component of blood–brain barrier (BBB), and has an important
position in the neurovascular unit. Its dysfunction and death after cerebral …

Background: Cerebral ischemia-reperfusion injury is caused by a blood reperfusion injury in
the ischemic brain and usually occurs in the treatment stage of ischemic disease, which can …

Background Cerebral ischemia/reperfusion injury (CIRI) is a sequence of pathophysiological
processes after blood recanalization in the patients with ischemic stroke, and has become …

Blood–brain barrier disruption is a critical pathological event in the progression of ischemic
stroke (IS). Most studies regarding the therapeutic potential of neferine (Nef) on IS have …

Objective: Taohong Siwu decoction (THSWD) is one of the classic prescriptions for
promoting blood circulation and removing blood stasis, and it has a good therapeutic effect …

Background: Intracerebral hemorrhage (ICH) is a major cause of death and disability
globally. As a type of secondary injury after ICH, treatment for cell death can promote the …