Oncogenic signaling pathways and hallmarks of cancer in Korean patients with acral melanoma

SR Moon, HJ Kim, Y Lee, YJ Lee, S Jung… - Computers in Biology …, 2023 - Elsevier
Acral melanoma (AM), a rare subtype of cutaneous melanoma, shows higher incidence in
Asians, including Koreans, than in Caucasians. However, the genetic modification …

Comparative transcriptomic analysis reveals differences in gene expression and regulatory pathways between nonacral and acral melanoma in Asian individuals

YJ Chiu, CY Li, TH Wang, H Ma… - The Journal of …, 2024 - Wiley Online Library
Melanoma predominantly occurs in White individuals, which is associated with factors such
as exposure to UV radiation and skin pigmentation. Despite its low incidence, melanoma is …

[HTML][HTML] Prognostic value of genetic aberrations and tumor immune microenvironment in primary acral melanoma

R Huang, G Shen, Y Ren, K Zheng, J Wang… - Journal of Translational …, 2023 - Springer
Background Acral melanoma (AM) is the most common subtype in Chinese melanoma
patients with a very poor prognosis. However, our understanding of the disease …

[HTML][HTML] The molecular landscape of primary acral melanoma: a multicenter study of the Italian melanoma intergroup (IMI)

L Elefanti, C Zamuner, P Del Fiore, C Stagni… - International Journal of …, 2021 - mdpi.com
Acral melanoma (AM) is a rare and aggressive subtype of melanoma affecting the palms,
soles, and nail apparatus with similar incidence among different ethnicities. AM is unrelated …

Mutational profiling of acral melanomas in Korean populations

JH Shim, HT Shin, J Park, JH Park… - Experimental …, 2017 - Wiley Online Library
The proportion of acral melanoma (AM) is much higher in Asian populations than in
Caucasian populations. Although mutational profiles associated with AM have been …

The mutational burden of acral melanoma revealed by whole‐genome sequencing and comparative analysis

SJ Furney, S Turajlic, G Stamp… - Pigment cell & …, 2014 - Wiley Online Library
Acral melanoma is a subtype of melanoma with distinct epidemiological, clinical and
mutational profiles. To define the genomic alterations in acral melanoma, we conducted …

Identification of genetic mutations related to invasion and metastasis of acral melanoma via whole‐exome sequencing

Y Lim, DY Lee - The Journal of Dermatology, 2021 - Wiley Online Library
Many studies have analyzed the genes related to melanoma. However, only a limited
number of studies have been conducted to identify the genes that are involved in the …

Integrative genomic profiling uncovers therapeutic targets of acral melanoma in Asian populations

Q Shi, L Liu, J Chen, W Zhang, W Guo, X Wang… - Clinical Cancer …, 2022 - AACR
Purpose: Acral melanoma is the major subtype of melanoma seen in Asian patients with
melanoma and is featured by its insidious onset and poor prognosis. The genomic study that …

[HTML][HTML] Clinical features, molecular pathology, and immune microenvironmental characteristics of acral melanoma

J Gui, Z Guo, D Wu - Journal of Translational Medicine, 2022 - Springer
Acral melanoma (AM) has unique biology as an aggressive subtype of melanoma. It is a
common subtype of melanoma in races with darker skin tones usually diagnosed at a later …

Whole genome and RNA sequencing reveal the distinct genomic landscape of acral melanoma.

Y Kong, Z Chi, L Si, X Sheng, C Cui, J Dai, M Ma, X Wu… - 2017 - ascopubs.org
9589 Background: Acral melanoma is a common subtype of melanoma in Asians with
extremely poor prognosis, and therapy strategy has not been clearly established for acral …