Oncogenic signaling pathways and hallmarks of cancer in Korean patients with acral melanoma
SR Moon, HJ Kim, Y Lee, YJ Lee, S Jung… - Computers in Biology …, 2023 - Elsevier
Acral melanoma (AM), a rare subtype of cutaneous melanoma, shows higher incidence in
Asians, including Koreans, than in Caucasians. However, the genetic modification …
Asians, including Koreans, than in Caucasians. However, the genetic modification …
Comparative transcriptomic analysis reveals differences in gene expression and regulatory pathways between nonacral and acral melanoma in Asian individuals
Melanoma predominantly occurs in White individuals, which is associated with factors such
as exposure to UV radiation and skin pigmentation. Despite its low incidence, melanoma is …
as exposure to UV radiation and skin pigmentation. Despite its low incidence, melanoma is …
[HTML][HTML] Prognostic value of genetic aberrations and tumor immune microenvironment in primary acral melanoma
R Huang, G Shen, Y Ren, K Zheng, J Wang… - Journal of Translational …, 2023 - Springer
Background Acral melanoma (AM) is the most common subtype in Chinese melanoma
patients with a very poor prognosis. However, our understanding of the disease …
patients with a very poor prognosis. However, our understanding of the disease …
[HTML][HTML] The molecular landscape of primary acral melanoma: a multicenter study of the Italian melanoma intergroup (IMI)
L Elefanti, C Zamuner, P Del Fiore, C Stagni… - International Journal of …, 2021 - mdpi.com
Acral melanoma (AM) is a rare and aggressive subtype of melanoma affecting the palms,
soles, and nail apparatus with similar incidence among different ethnicities. AM is unrelated …
soles, and nail apparatus with similar incidence among different ethnicities. AM is unrelated …
Mutational profiling of acral melanomas in Korean populations
The proportion of acral melanoma (AM) is much higher in Asian populations than in
Caucasian populations. Although mutational profiles associated with AM have been …
Caucasian populations. Although mutational profiles associated with AM have been …
The mutational burden of acral melanoma revealed by whole‐genome sequencing and comparative analysis
SJ Furney, S Turajlic, G Stamp… - Pigment cell & …, 2014 - Wiley Online Library
Acral melanoma is a subtype of melanoma with distinct epidemiological, clinical and
mutational profiles. To define the genomic alterations in acral melanoma, we conducted …
mutational profiles. To define the genomic alterations in acral melanoma, we conducted …
Identification of genetic mutations related to invasion and metastasis of acral melanoma via whole‐exome sequencing
Y Lim, DY Lee - The Journal of Dermatology, 2021 - Wiley Online Library
Many studies have analyzed the genes related to melanoma. However, only a limited
number of studies have been conducted to identify the genes that are involved in the …
number of studies have been conducted to identify the genes that are involved in the …
Integrative genomic profiling uncovers therapeutic targets of acral melanoma in Asian populations
Q Shi, L Liu, J Chen, W Zhang, W Guo, X Wang… - Clinical Cancer …, 2022 - AACR
Purpose: Acral melanoma is the major subtype of melanoma seen in Asian patients with
melanoma and is featured by its insidious onset and poor prognosis. The genomic study that …
melanoma and is featured by its insidious onset and poor prognosis. The genomic study that …
[HTML][HTML] Clinical features, molecular pathology, and immune microenvironmental characteristics of acral melanoma
J Gui, Z Guo, D Wu - Journal of Translational Medicine, 2022 - Springer
Acral melanoma (AM) has unique biology as an aggressive subtype of melanoma. It is a
common subtype of melanoma in races with darker skin tones usually diagnosed at a later …
common subtype of melanoma in races with darker skin tones usually diagnosed at a later …
Whole genome and RNA sequencing reveal the distinct genomic landscape of acral melanoma.
Y Kong, Z Chi, L Si, X Sheng, C Cui, J Dai, M Ma, X Wu… - 2017 - ascopubs.org
9589 Background: Acral melanoma is a common subtype of melanoma in Asians with
extremely poor prognosis, and therapy strategy has not been clearly established for acral …
extremely poor prognosis, and therapy strategy has not been clearly established for acral …
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