Several different reactive oxygen species (ROS) are generated in vivo. They have roles in
the development of certain human diseases whilst also performing physiological functions …

Aging is accompanied by the decline of organismal functions and a series of prominent
hallmarks, including genetic and epigenetic alterations. These aging-associated epigenetic …

The geroscience hypothesis proposes that therapy to slow or reverse molecular changes
that occur with aging can delay or prevent multiple chronic diseases and extend healthy …

Mitochondria play a pivotal role in bioenergetics and respiratory functions, which are
essential for the numerous biochemical processes underpinning cell viability. Mitochondrial …

Aging is a physiological process mediated by numerous biological and genetic pathways,
which are directly linked to lifespan and are a driving force for all age-related diseases …

Nonalcoholic fatty liver disease (NAFLD) has emerged as the most common chronic liver
disease worldwide and is strongly associated with the presence of oxidative stress …

An epidemic of obesity has affected large portions of the world, increasing the risk of
developing many different age-associated diseases, including cancer, cardiovascular …

Effects of Intermittent Fasting on Health and Aging Evidence is accumulating that eating in a
6-hour period and fasting for 18 hours can trigger a metabolic switch from glucose-based to …

Nutriments have been deemed to impact all physiopathologic processes. Recent evidences
in molecular medicine and clinical trials have demonstrated that adequate nutrition …

Ageing is characterized by the functional decline of tissues and organs and the increased
risk of ageing-associated disorders. Several 'rejuvenating'interventions have been proposed …