Evidence is provided for a new conceptualization of the connectivity and functions of the
cingulate cortex in emotion, action, and memory. The anterior cingulate cortex receives …

The orbitofrontal cortex and amygdala are involved in emotion and in motivation, but the
relationship between these functions performed by these brain structures is not clear. To …

The orbitofrontal cortex in primates including humans is the key brain area in emotion, and
in the representation of reward value and in non-reward, that is not obtaining an expected …

The outcome of a decision is often uncertain, and outcomes can vary over repeated
decisions. Whether decision outcomes should substantially affect behaviour and learning …

Every day we make decisions about what to seek out and what to avoid. For instance, we
might decide to look for a tasty sandwich for lunch, choose to spend time with a friend, or …

The nucleus reuniens of the thalamus (RE) is a key component of an extensive network of
hippocampal and cortical structures and is a fundamental substrate for cognition. A common …

Adaptive behaviour crucially depends on flexible decision-making, which in mammals relies
on the frontal cortex, specifically the orbitofrontal cortex (OFC),,,,,,,–. How OFC encodes …

Adaptive reward-related decision making requires accurate prospective consideration of the
specific outcome of each option and its current desirability. These mental simulations are …

The estimated values of choices, and therefore decision-making based on those values, are
influenced by both the chance that the chosen items or goods can be obtained (availability) …

The value of an anticipated rewarding event is a crucial component of the decision to
engage in its pursuit. But little is known of the networks responsible for encoding and …