Toxicity of zearalenone and its nutritional intervention by natural products

S Jing, C Liu, J Zheng, Z Dong, N Guo - Food & Function, 2022 - pubs.rsc.org
Zearalenone (ZEN) is a toxic secondary metabolite mainly produced by fungi of the genus
Fusarium, and is often present in various food and feed ingredients such as corn and wheat …

Toxicodynamic of combined mycotoxins: MicroRNAs and acute‐phase proteins as diagnostic biomarkers

B Murtaza, X Li, MY Nawaz, MK Saleemi… - … Reviews in Food …, 2024 - Wiley Online Library
Mycotoxins, ubiquitous contaminants in food, present a global threat to human health and
well‐being. Mitigation efforts, such as the implementation of sound agricultural practices …

Protective effects of lycopene against zearalenone-induced reproductive toxicity in early pregnancy through anti-inflammatory, antioxidant and anti-apoptotic effects

J Kang, Y Li, Z Ma, Y Wang, W Zhu, G Jiang - Food and Chemical …, 2023 - Elsevier
Zearalenone is a mycotoxin that is widely present in feed and raw materials and can cause
severe reproductive toxicity. Lycopene is a natural carotenoid with antioxidant and anti …

[HTML][HTML] Zearalenone exposure triggered cecal physical barrier injury through the TGF-β1/Smads signaling pathway in weaned piglets

P Zhang, C Jing, M Liang, S Jiang, L Huang, N Jiao… - Toxins, 2021 - mdpi.com
This study aims to investigate the effects of exposure to different dosages of zearalenone
(ZEA) on cecal physical barrier functions and its mechanisms based on the TGF-β1/Smads …

Zearalenone promotes follicle development through activating the SIRT1/PGC-1α signaling pathway in the ovaries of weaned gilts

B Wan, L Huang, C Jing, Y Li, N Jiao… - Journal of Animal …, 2022 - academic.oup.com
This study aimed to investigate the effect of zearalenone (ZEA) exposure on follicular
development in weaned gilts, and its mechanism based on the silent information regulator 1 …

LncRNA profiles of Cyanidin-3-O-glucoside ameliorated Zearalenone-induced damage in porcine granulosa cells

X Li, F Zhang, J Wang, Y Feng, S Zhang, L Li, J Tan… - Gene, 2023 - Elsevier
Long non-coding RNA (lncRNA), a class of RNA molecules with transcripts longer than 200
nt, is crucial for maintaining animal reproductive function. Zearalenone (ZEN) damaged …

[HTML][HTML] Exposure to Low Zearalenone Doses and Changes in the Homeostasis and Concentrations of Endogenous Hormones in Selected Steroid-Sensitive Tissues …

M Gajęcka, Ł Zielonka, A Babuchowski, MT Gajęcki - Toxins, 2022 - mdpi.com
This study was undertaken to analyze whether prolonged exposure to low-dose
zearalenone (ZEN) mycotoxicosis affects the concentrations of ZEN, α-zearalenol (α-ZEL) …

[HTML][HTML] Immunohistochemical expression (IE) of oestrogen receptors in the intestines of prepubertal gilts exposed to zearalenone

M Gajęcka, I Otrocka-Domagała, P Brzuzan… - Toxins, 2023 - mdpi.com
This study was conducted to determine if a low monotonic dose of zearalenone (ZEN) affects
the immunohistochemical expression (IE) of oestrogen receptor alpha (ERα) and oestrogen …

[HTML][HTML] Quantitative Proteomic Analysis of Zearalenone Exposure on Uterine Development in Weaned Gilts

X Liu, Z Wang, Y Jiang, L Huang, X Yuan, Y Li, N Jiao… - Toxins, 2022 - mdpi.com
The aim of this study was to explore the effect of zearalenone (ZEA) exposure on uterine
development in weaned gilts by quantitative proteome analysis with tandem mass …

[HTML][HTML] Alleviative Effect of Rutin on Zearalenone-Induced Reproductive Toxicity in Male Mice by Preventing Spermatogenic Cell Apoptosis and Modulating Gene …

H Sayed, Q Zhang, Y Tang, Y Wang, Y Guo, J Zhang… - Toxins, 2024 - mdpi.com
Zearalenone (ZEN) is a non-steroidal estrogenic mycotoxin found in many agricultural
products and can cause reproductive disorders, mainly affecting spermatogenesis in male …