Hyperinflammatory immune response and COVID-19: a double edged sword

LY Tan, TV Komarasamy… - Frontiers in …, 2021 - frontiersin.org
The coronavirus disease-19 (COVID-19) elicited by the severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) has caused devastating health, economic and social impact …

The mechanism underlying extrapulmonary complications of the coronavirus disease 2019 and its therapeutic implication

Q Ning, D Wu, X Wang, D Xi, T Chen, G Chen… - Signal transduction and …, 2022 - nature.com
Abstract The coronavirus disease 2019 (COVID-19) is a highly transmissible disease
caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that poses a …

SARS-CoV-2 viral persistence in lung alveolar macrophages is controlled by IFN-γ and NK cells

N Huot, C Planchais, P Rosenbaum, V Contreras… - Nature …, 2023 - nature.com
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) RNA generally becomes
undetectable in upper airways after a few days or weeks postinfection. Here we used a …

Interleukin-6, CXCL10 and infiltrating macrophages in COVID-19-related cytokine storm: not one for all but all for one!

F Coperchini, L Chiovato, M Rotondi - Frontiers in immunology, 2021 - frontiersin.org
SARS-COV-2 virus is responsible for the ongoing devastating pandemic. Since the early
phase of the pandemic, the “cytokine-storm” appeared a peculiar aspect of SARS-COV-2 …

Honeysuckle (Lonicera japonica) and Huangqi (Astragalus membranaceus) Suppress SARS-CoV-2 Entry and COVID-19 Related Cytokine Storm in Vitro

YC Yeh, LH Doan, ZY Huang, LW Chu… - Frontiers in …, 2022 - frontiersin.org
COVID-19 is threatening human health worldwide but no effective treatment currently exists
for this disease. Current therapeutic strategies focus on the inhibition of viral replication or …

COVID-19 and rheumatoid arthritis crosstalk: emerging association, therapeutic options and challenges

S Dewanjee, R Kandimalla, RS Kalra, C Valupadas… - Cells, 2021 - mdpi.com
Hyperactivation of immune responses resulting in excessive release of pro-inflammatory
mediators in alveoli/lung structures is the principal pathological feature of coronavirus …

Diverse immunological factors influencing pathogenesis in patients with COVID-19: a review on viral dissemination, immunotherapeutic options to counter cytokine …

AA Rabaan, SH Al-Ahmed, MA Garout, AM Al-Qaaneh… - Pathogens, 2021 - mdpi.com
The pathogenesis of coronavirus disease 2019 (COVID-19), caused by severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2), is still not fully unraveled. Though …

A systematic review and meta-analysis of the association between the neutrophil, lymphocyte, and platelet count, neutrophil-to-lymphocyte ratio, and platelet-to …

A Zinellu, AA Mangoni - Expert Review of Clinical Immunology, 2022 - Taylor & Francis
Background and aims Severe manifestations of coronavirus disease 2019 (COVID-19) are
associated with alterations in blood cells that regulate immunity, inflammation, and …

Antiviral molecular targets of essential oils against SARS-CoV-2: A systematic review

M Iqhrammullah, DR Rizki, A Purnama, TF Duta… - Scientia …, 2023 - mdpi.com
Essential oils are potential therapeutics for coronavirus disease 2019 (COVID-19), in which
some of the volatile compounds of essential oils have been well known for their broad …

[HTML][HTML] Biomarkers of the ageing immune system and their association with frailty–A systematic review

ET Van Hoi, NA De Glas, JEA Portielje… - Experimental …, 2023 - Elsevier
Introduction Ageing is associated with several physiological changes, including changes in
the immune system. Age-related changes in the innate and adaptive immune system are …