From rabbit antibody repertoires to rabbit monoclonal antibodies

J Weber, H Peng, C Rader - Experimental & molecular medicine, 2017 - nature.com
In this review, we explain why and how rabbit monoclonal antibodies have become
outstanding reagents for laboratory research and increasingly for diagnostic and therapeutic …

Insights into the chicken IgY with emphasis on the generation and applications of chicken recombinant monoclonal antibodies

W Lee, AS Atif, SC Tan, CH Leow - Journal of immunological methods, 2017 - Elsevier
The advantages of chicken (Gallus gallus domesticus) antibodies as immunodiagnostic and
immunotherapeutic biomolecules has only been recently recognized. Even so, chicken …

Identification and tracking of antiviral drug combinations

A Ianevski, R Yao, S Biza, E Zusinaite, A Männik, G Kivi… - Viruses, 2020 - mdpi.com
Combination therapies have become a standard for the treatment for HIV and hepatitis C
virus (HCV) infections. They are advantageous over monotherapies due to better efficacy …

Heterotypic interactions drive antibody synergy against a malaria vaccine candidate

RJ Ragotte, D Pulido, AM Lias, D Quinkert… - Nature …, 2022 - nature.com
Understanding mechanisms of antibody synergy is important for vaccine design and
antibody cocktail development. Examples of synergy between antibodies are well …

Broadly neutralizing humanized SARS-CoV-2 antibody binds to a conserved epitope on spike and provides antiviral protection through inhalation-based delivery in …

P Hermet, B Delache, C Herate, E Wolf, G Kivi… - PLoS …, 2023 - journals.plos.org
The COVID-19 pandemic represents a global challenge that has impacted and is expected
to continue to impact the lives and health of people across the world for the foreseeable …

Seven classes of antiviral agents

A Ianevski, S Ahmad, K Anunnitipat… - Cellular and Molecular …, 2022 - Springer
The viral epidemics and pandemics have stimulated the development of known and the
discovery of novel antiviral agents. About a hundred mono-and combination antiviral drugs …

A method for the isolation and characterization of functional murine monoclonal antibodies by single B cell cloning

S Carbonetti, BG Oliver, V Vigdorovich… - Journal of …, 2017 - Elsevier
Monoclonal antibody technologies have enabled dramatic advances in immunology, the
study of infectious disease, and modern medicine over the past 40 years. However, many …

[HTML][HTML] Targeting a cancer-specific LYPD3 glycoform for tumor therapy

T Neumann, E Hartung, J Gellert, L Weiß… - Frontiers in Drug …, 2023 - frontiersin.org
One of the most drastic changes in cancer is the altered glycosylation of proteins and lipids,
giving rise to truncated O-glycans like the Thomsen Friedenreich (TF) or Thomsen nouvelle …

Advances in the isolation of specific monoclonal rabbit antibodies

Z Zhang, H Liu, Q Guan, L Wang, H Yuan - Frontiers in Immunology, 2017 - frontiersin.org
The rabbit monoclonal antibodies (mAbs) have advantages in pharmaceuticals and
diagnostics with high affinity and specificity. During the past decade, many techniques have …

Antibodies targeting the shared cytokine receptor IL-1 receptor accessory protein invoke distinct mechanisms to block all cytokine signaling

JK Fields, EJ Gyllenbäck, M Bogacz, J Obi, GS Birkedal… - Cell Reports, 2024 - cell.com
Summary Interleukin-1 (IL-1)-family cytokines are potent modulators of inflammation,
coordinating a vast array of immunological responses across innate and adaptive immune …