[PDF][PDF] The vascular perspective on acute and chronic lung disease
I Borek, A Birnhuber, NF Voelkel… - Journal of Clinical …, 2023 - Am Soc Clin Investig
The pulmonary vasculature has been frequently overlooked in acute and chronic lung
diseases, such as acute respiratory distress syndrome (ARDS), pulmonary fibrosis (PF), and …
diseases, such as acute respiratory distress syndrome (ARDS), pulmonary fibrosis (PF), and …
Cigarette smoke induces the ROS accumulation and iNOS activation through deactivation of Nrf-2/SIRT3 axis to mediate the human bronchial epithelium ferroptosis
Y Zi, X Wang, Y Zi, H Yu, Y Lan, Y Fan, C Ren… - Free Radical Biology …, 2023 - Elsevier
Cigarette smoke (CS)-induced oxidative stress drives the pathogenesis of respiratory
diseases, in which the activation and accumulation of reactive oxygen species (ROS) play …
diseases, in which the activation and accumulation of reactive oxygen species (ROS) play …
[HTML][HTML] Myeloid-derived suppressor cells and pulmonary hypertension
H Zhang, QW Li, YY Li, X Tang, L Gu… - Frontiers in …, 2023 - frontiersin.org
Pulmonary hypertension (PH) is a chronic pulmonary vascular disorder characterized by an
increase in pulmonary vascular resistance and pulmonary arterial pressure. The detailed …
increase in pulmonary vascular resistance and pulmonary arterial pressure. The detailed …
Nicotine promotes e-cigarette vapour-induced lung inflammation and structural alterations
ET Roxlau, O Pak, S Hadzic… - European …, 2023 - Eur Respiratory Soc
Background Electronic cigarette (e-cigarette) vapour is gaining popularity as an alternative
to tobacco smoking and can induce acute lung injury. However, the specific role of nicotine …
to tobacco smoking and can induce acute lung injury. However, the specific role of nicotine …
Aldehyde Dehydrogenase 2 (ALDH2) Elicits Protection against Pulmonary Hypertension via Inhibition of ERK1/2‐Mediated Autophagy
S Chang, J Wu, J Jin, H Shi, R Gao, X Li… - Oxidative medicine …, 2022 - Wiley Online Library
Pulmonary hypertension (PH) is caused by chronic hypoxia that induces the migration and
proliferation of pulmonary arterial smooth muscle cells (PASMCs), eventually resulting in …
proliferation of pulmonary arterial smooth muscle cells (PASMCs), eventually resulting in …
CEACAM6 as a Novel Therapeutic Target to Boost HO-1—mediated Antioxidant Defense in COPD
CY Wu, A Cilic, O Pak, RC Dartsch… - American Journal of …, 2023 - atsjournals.org
Rationale: Tobacco smoking and air pollution are primary causes of chronic obstructive
pulmonary disease (COPD). However, only a minority of smokers develop COPD. The …
pulmonary disease (COPD). However, only a minority of smokers develop COPD. The …
[HTML][HTML] Tensions in taxonomies: current understanding and future directions in the pathobiologic basis and treatment of group 1 and group 3 pulmonary hypertension
S Gu, K Goel, LM Forbes, VO Kheyfets… - Comprehensive …, 2023 - ncbi.nlm.nih.gov
In the over 100 years since the recognition of pulmonary hypertension (PH), immense
progress and significant achievements have been made with regard to understanding the …
progress and significant achievements have been made with regard to understanding the …
[HTML][HTML] GPS2 ameliorates cigarette smoking-induced pulmonary vascular remodeling by modulating the ras-Raf-ERK axis
T Hu, C Mu, Y Li, W Hao, X Yu, Y Wang, W Han… - Respiratory Research, 2024 - Springer
Background Mitogen-activated protein kinase (MAPK) signaling-mediated smoking-
associated pulmonary vascular remodeling (PVR) plays an important role in the …
associated pulmonary vascular remodeling (PVR) plays an important role in the …
Impact of Smoking and Chronic Obstructive Pulmonary Disease on All-Cause, Respiratory, and Cardio-Cerebrovascular Mortality
HR Kang, SJ Kim, JG Nam, YS Park… - International Journal of …, 2024 - Taylor & Francis
Introduction Mortality differences in chronic obstructive pulmonary disease (COPD) between
nonsmokers and smokers remain unclear. We compared the risk of death associated with …
nonsmokers and smokers remain unclear. We compared the risk of death associated with …
[HTML][HTML] Unleashing the Potential of Nrf2: A Novel Therapeutic Target for Pulmonary Vascular Remodeling
Q Fang, Y Bai, S Hu, J Ding, L Liu, M Dai, J Qiu, L Wu… - Antioxidants, 2023 - mdpi.com
Pulmonary vascular remodeling, characterized by the thickening of all three layers of the
blood vessel wall, plays a central role in the pathogenesis of pulmonary hypertension (PH) …
blood vessel wall, plays a central role in the pathogenesis of pulmonary hypertension (PH) …