Inflammation after spinal cord injury: a review of the critical timeline of signaling cues and cellular infiltration
DJ Hellenbrand, CM Quinn, ZJ Piper… - Journal of …, 2021 - Springer
Traumatic spinal cord injury (SCI) is a devastating neurological condition that results in a
loss of motor and sensory function. Although extensive research to develop treatments for …
loss of motor and sensory function. Although extensive research to develop treatments for …
[HTML][HTML] Traumatic spinal cord injury: an overview of pathophysiology, models and acute injury mechanisms
A Alizadeh, SM Dyck, S Karimi-Abdolrezaee - Frontiers in neurology, 2019 - frontiersin.org
Traumatic spinal cord injury (SCI) is a life changing neurological condition with substantial
socioeconomic implications for patients and their care-givers. Recent advances in medical …
socioeconomic implications for patients and their care-givers. Recent advances in medical …
Review of advances in electrospinning-based strategies for spinal cord regeneration
Spinal cord injury (SCI) is a devastating neurological condition, commonly leading to
physical and mental deficiencies, pain, other complications, and even death. Most recently …
physical and mental deficiencies, pain, other complications, and even death. Most recently …
[HTML][HTML] Spinal cord injury scarring and inflammation: therapies targeting glial and inflammatory responses
MB Orr, JC Gensel - Neurotherapeutics, 2018 - Elsevier
Deficits in neuronal function are a hallmark of spinal cord injury (SCI) and therapeutic efforts
are often focused on central nervous system (CNS) axon regeneration. However, secondary …
are often focused on central nervous system (CNS) axon regeneration. However, secondary …
Cell transplantation therapy for spinal cord injury
Spinal cord injury can lead to severe motor, sensory and autonomic dysfunction. Currently,
there is no effective treatment for the injured spinal cord. The transplantation of Schwann …
there is no effective treatment for the injured spinal cord. The transplantation of Schwann …
A DAMP-scavenging, IL-10-releasing hydrogel promotes neural regeneration and motor function recovery after spinal cord injury
Spinal cord injury (SCI) creates an inflammatory microenvironment characterized by
damage-associated molecular patterns (DAMPs) and immune cell activation that exacerbate …
damage-associated molecular patterns (DAMPs) and immune cell activation that exacerbate …
Spinal cord injury: molecular mechanisms and therapeutic interventions
X Hu, W Xu, Y Ren, Z Wang, X He, R Huang… - … and Targeted Therapy, 2023 - nature.com
Spinal cord injury (SCI) remains a severe condition with an extremely high disability rate.
The challenges of SCI repair include its complex pathological mechanisms and the …
The challenges of SCI repair include its complex pathological mechanisms and the …
The PI3K/AKT signalling pathway in inflammation, cell death and glial scar formation after traumatic spinal cord injury: Mechanisms and therapeutic opportunities
X He, Y Li, B Deng, A Lin, G Zhang, M Ma… - Cell …, 2022 - Wiley Online Library
Abstract Objects Traumatic spinal cord injury (TSCI) causes neurological dysfunction below
the injured segment of the spinal cord, which significantly impacts the quality of life in …
the injured segment of the spinal cord, which significantly impacts the quality of life in …
[HTML][HTML] Anisotropic scaffolds for peripheral nerve and spinal cord regeneration
The treatment of long-gap (> 10 mm) peripheral nerve injury (PNI) and spinal cord injury
(SCI) remains a continuous challenge due to limited native tissue regeneration capabilities …
(SCI) remains a continuous challenge due to limited native tissue regeneration capabilities …
Advances in biomaterial‐based spinal cord injury repair
H Shen, C Fan, Z You, Z Xiao… - Advanced Functional …, 2022 - Wiley Online Library
Spinal cord injury (SCI) often leads to the loss of motor and sensory functions and is a major
challenge in neurological clinical practice. Understanding the pathophysiological changes …
challenge in neurological clinical practice. Understanding the pathophysiological changes …