[HTML][HTML] Acetate revisited: a key biomolecule at the nexus of metabolism, epigenetics, and oncogenesis–part 2: acetate and ACSS2 in health and disease

JR Moffett, N Puthillathu, R Vengilote… - Frontiers in …, 2020 - frontiersin.org
Acetate, the shortest chain fatty acid, has been implicated in providing health benefits
whether it is derived from the diet or is generated from microbial fermentation of fiber in the …

Lipid‐induced mechanisms of metabolic syndrome

YK Denisenko, OY Kytikova… - Journal of …, 2020 - Wiley Online Library
Metabolic syndrome (MetS) has a worldwide tendency to increase and depends on many
components, which explains the complexity of diagnosis, approaches to the prevention, and …

[HTML][HTML] A gut butyrate‑producing bacterium Butyricicoccus pullicaecorum regulates short‑chain fatty acid transporter and receptor to reduce the progression of 1,2 …

SC Chang, MH Shen, CY Liu, CM Pu… - Oncology …, 2020 - spandidos-publications.com
Gut microbes influence tumor development and progression in the intestines and may
provide a novel paradigm for the treatment of colorectal cancer (CRC). Gut dysbiosis may be …

[HTML][HTML] Role of short chain fatty acids in gut health and possible therapeutic approaches in inflammatory bowel diseases

MAF Caetano, P Castelucci - World Journal of Clinical Cases, 2022 - ncbi.nlm.nih.gov
Inflammatory bowel diseases (IBDs) are characterized by inflammation in the
gastrointestinal tract and include Ulcerative Colitis and Crohn's Disease. These diseases …

Fecal virome transfer improves proliferation of commensal gut Akkermansia muciniphila and unexpectedly enhances the fertility rate in laboratory mice

TS Rasmussen, CMJ Mentzel, MR Danielsen… - Gut …, 2023 - Taylor & Francis
Probiotics are intended to improve gastrointestinal health when consumed. However, the
probiotics marketed today only colonize the densely populated gut to a limited extent …

Indolepropionic acid reduces obesity‐induced metabolic dysfunction through colonic barrier restoration mediated via tuft cell‐derived IL‐25

L Chen, Y Yang, S Sun, Y Xie, C Pan, M Li… - The FEBS …, 2022 - Wiley Online Library
Previous studies have indicated that indolepropionic acid (IPA), derived from dietary
tryptophan via gut microbiota conversion, is negatively correlated with type 2 diabetes …

The interplay of sex steroids, the immune response, and the intestinal microbiota

F Pace, PI Watnick - Trends in Microbiology, 2021 - cell.com
The role of sex steroids in mammalian maturation is well established. Recently, it has been
increasingly appreciated that sex steroids also play an important role in the propensity of …

[HTML][HTML] Low-dose ethanol consumption inhibits neutrophil extracellular traps formation to alleviate rheumatoid arthritis

L Jin, Z Zhang, P Pan, Y Zhao, M Zhou, L Liu… - Communications …, 2023 - nature.com
Rheumatoid arthritis (RA) is a chronic systemic autoimmune disease. Ethanol consumption
has been reported to reduce morbidity in RA patients, but the mechanism behind it remains …

[HTML][HTML] Free fatty acid receptor 4 deletion attenuates colitis by modulating Treg Cells via ZBED6-IL33 pathway

S Zhu, J Zhang, X Jiang, W Wang, YQ Chen - EBioMedicine, 2022 - thelancet.com
Background Inflammatory bowel disease (IBD) has complex genetic and environmental
aspects, and free fatty acid receptors (FFARs) may bridge genetic and dietary aspects …

The role of gut microbiota and probiotics in preventing, treating, and boosting the immune system in colorectal cancer

F Masheghati, MR Asgharzadeh, A Jafari, N Masoudi… - Life Sciences, 2024 - Elsevier
The gut microbiome plays a significant role in developing colorectal cancer (CRC). The gut
microbiome usually acts as a protective barrier against harmful pathogens and infections in …