A unifying perspective on neural manifolds and circuits for cognition
Two different perspectives have informed efforts to explain the link between the brain and
behaviour. One approach seeks to identify neural circuit elements that carry out specific …
behaviour. One approach seeks to identify neural circuit elements that carry out specific …
The digital twin brain: A bridge between biological and artificial intelligence
In recent years, advances in neuroscience and artificial intelligence have paved the way for
unprecedented opportunities to understand the complexity of the brain and its emulation …
unprecedented opportunities to understand the complexity of the brain and its emulation …
Coupling of pupil-and neuronal population dynamics reveals diverse influences of arousal on cortical processing
Fluctuations in arousal, controlled by subcortical neuromodulatory systems, continuously
shape cortical state, with profound consequences for information processing. Yet, how …
shape cortical state, with profound consequences for information processing. Yet, how …
[HTML][HTML] Choice selective inhibition drives stability and competition in decision circuits
During perceptual decision-making, the firing rates of cortical neurons reflect upcoming
choices. Recent work showed that excitatory and inhibitory neurons are equally selective for …
choices. Recent work showed that excitatory and inhibitory neurons are equally selective for …
Circuit mechanisms for the chemical modulation of cortex-wide network interactions and behavioral variability
Influential theories postulate distinct roles of catecholamines and acetylcholine in cognition
and behavior. However, previous physiological work reported similar effects of these …
and behavior. However, previous physiological work reported similar effects of these …
[HTML][HTML] Distinct hierarchical alterations of intrinsic neural timescales account for different manifestations of psychosis
Hierarchical perceptual-inference models of psychosis may provide a holistic framework for
understanding psychosis in schizophrenia including heterogeneity in clinical presentations …
understanding psychosis in schizophrenia including heterogeneity in clinical presentations …
Attractor-like dynamics in belief updating in schizophrenia
Subjects with a diagnosis of schizophrenia (Scz) overweight unexpected evidence in
probabilistic inference: such evidence becomes “aberrantly salient.” A neurobiological …
probabilistic inference: such evidence becomes “aberrantly salient.” A neurobiological …
[HTML][HTML] Proactive and reactive accumulation-to-bound processes compete during perceptual decisions
L Hernández-Navarro, A Hermoso-Mendizabal… - Nature …, 2021 - nature.com
Standard models of perceptual decision-making postulate that a response is triggered in
reaction to stimulus presentation when the accumulated stimulus evidence reaches a …
reaction to stimulus presentation when the accumulated stimulus evidence reaches a …
[HTML][HTML] The thalamus in psychosis spectrum disorder
A Anticevic, MM Halassa - Frontiers in Neuroscience, 2023 - frontiersin.org
Psychosis spectrum disorder (PSD) affects 1% of the world population and results in a
lifetime of chronic disability, causing devastating personal and economic consequences …
lifetime of chronic disability, causing devastating personal and economic consequences …
[HTML][HTML] Catecholamines alter the intrinsic variability of cortical population activity and perception
The ascending modulatory systems of the brain stem are powerful regulators of global brain
state. Disturbances of these systems are implicated in several major neuropsychiatric …
state. Disturbances of these systems are implicated in several major neuropsychiatric …