Lipid droplet biogenesis and functions in health and disease

A Zadoorian, X Du, H Yang - Nature Reviews Endocrinology, 2023 - nature.com
Ubiquitous yet unique, lipid droplets are intracellular organelles that are increasingly being
recognized for their versatility beyond energy storage. Advances uncovering the intricacies …

New perspectives in diabetic neuropathy

SA Eid, AE Rumora, B Beirowski, DL Bennett, J Hur… - Neuron, 2023 - cell.com
Diabetes prevalence continues to climb with the aging population. Type 2 diabetes (T2D),
which constitutes most cases, is metabolically acquired. Diabetic peripheral neuropathy …

[HTML][HTML] Global, regional, and national burden of diabetes from 1990 to 2021, with projections of prevalence to 2050: a systematic analysis for the Global Burden of …

KL Ong, LK Stafford, SA McLaughlin, EJ Boyko… - The Lancet, 2023 - thelancet.com
Background Diabetes is one of the leading causes of death and disability worldwide, and
affects people regardless of country, age group, or sex. Using the most recent evidentiary …

Regulation of biological processes by intrinsically chiral engineered materials

B Ma, A Bianco - Nature Reviews Materials, 2023 - nature.com
Chirality has a key role in the synthesis of biomolecules and the development of life.
Although the effects of many chiral molecules or materials on biological processes have …

Artificial intelligence in ophthalmology: The path to the real-world clinic

Z Li, L Wang, X Wu, J Jiang, W Qiang, H Xie… - Cell Reports …, 2023 - cell.com
Artificial intelligence (AI) has great potential to transform healthcare by enhancing the
workflow and productivity of clinicians, enabling existing staff to serve more patients …

Dissecting causal associations of type 2 diabetes with 111 types of ocular conditions: a Mendelian randomization study

R Chen, S Xu, Y Ding, L Li, C Huang, M Bao… - Frontiers in …, 2023 - frontiersin.org
Background Despite the well-established findings of a higher incidence of retina-related eye
diseases in patients with diabetes, there is less investigation into the causal relationship …

Non-Alcoholic Fatty Liver Disease or Type 2 Diabetes Mellitus—The Chicken or the Egg Dilemma

M Kosmalski, A Śliwińska, J Drzewoski - Biomedicines, 2023 - mdpi.com
In clinical practice, we often deal with patients who suffer from non-alcoholic fatty liver
disease (NAFLD) concurrent with type 2 diabetes mellitus (T2DM). The etiopathogenesis of …

Integrated management of HIV, diabetes, and hypertension in sub-Saharan Africa (INTE-AFRICA): a pragmatic cluster-randomised, controlled trial

S Kivuyo, J Birungi, J Okebe, D Wang, K Ramaiya… - The Lancet, 2023 - thelancet.com
Summary Background In sub-Saharan Africa, health-care provision for chronic conditions is
fragmented. The aim of this study was to determine whether integrated management of HIV …

Oral nanomedicine biointeractions in the gastrointestinal tract in health and disease

C Chen, A Beloqui, Y Xu - Advanced drug delivery reviews, 2023 - Elsevier
Oral administration is the preferred route of administration based on the convenience for and
compliance of the patient. Oral nanomedicines have been developed to overcome the …

[PDF][PDF] Efficacy and safety of mazdutide in chinese patients with type 2 diabetes: A randomized, double-blind, placebo-controlled phase 2 trial

B Zhang, Z Cheng, J Chen, X Zhang, D Liu… - Diabetes …, 2024 - Am Diabetes Assoc
OBJECTIVE We conducted a randomized, double-blind, placebo-controlled phase 2 trial to
evaluate the efficacy and safety of mazdutide, a once-weekly glucagon-like peptide 1 and …