Camptothecin-based prodrug nanomedicines for cancer therapy
H Jiang, RS Zhang, C Wang, J Yu, Z Guo - Nanoscale, 2023 - pubs.rsc.org
Camptothecin (CPT) is a cytotoxic alkaloid that attenuates the replication cancer cells via
blocking DNA topoisomerase 1. Despite its encouraging and wide spectrum antitumour …
blocking DNA topoisomerase 1. Despite its encouraging and wide spectrum antitumour …
[HTML][HTML] Metal-based nanoparticles in cancer therapy: exploring photodynamic therapy and its interplay with regulated cell death pathways
Photodynamic therapy (PDT) represents a non-invasive treatment strategy currently utilized
in the clinical management of selected cancers and infections. This technique is predicated …
in the clinical management of selected cancers and infections. This technique is predicated …
Engineering CAR-NK cell derived exosome disguised nano-bombs for enhanced HER2 positive breast cancer brain metastasis therapy
B Tao, R Du, X Zhang, B Jia, Y Gao, Y Zhao… - Journal of Controlled …, 2023 - Elsevier
HER2-positive breast cancer brain metastasis (HER2+ BCBM) is a refractory malignancy
with a high recurrence rate and poor prognosis. The efficacies of conventional treatments …
with a high recurrence rate and poor prognosis. The efficacies of conventional treatments …
A swellable hydrogel microneedle based on cerium-metal organic frame composite nanozyme for detection of biomarkers
J Zhao, J Lv, G Ling, P Zhang - International Journal of Biological …, 2024 - Elsevier
Skin interstitial fluid (ISF) has been an alternative source in the field of biomarkers analysis.
This work developed swellable hydrogel microneedles (MNs) composed of polyvinyl alcohol …
This work developed swellable hydrogel microneedles (MNs) composed of polyvinyl alcohol …
Application of singlet oxygen-activatable nanocarriers to boost X-ray-induced photodynamic therapy and cascaded ferroptosis for breast cancer treatment
B Zhang, H Liu, Y Wang, Y Zhang… - Journal of Materials …, 2023 - pubs.rsc.org
Ferroptosis has appealing antitumor potential that is mainly based on the accumulation of
lipid peroxide to a lethal level. The cytotoxic singlet oxygen (1O2) generated from nanoscale …
lipid peroxide to a lethal level. The cytotoxic singlet oxygen (1O2) generated from nanoscale …
“Two-Stage Rocket-Propelled” Strategy Boosting Theranostic Efficacy with Mitochondria-Specific Type I–II Photosensitizers
X Yang, X Zhang, Z Yang, L Cheng, X Liu… - … applied materials & …, 2024 - ACS Publications
Imaging-guided photodynamic therapy (PDT) holds great potential for tumor therapy.
However, achieving the synergistic enhancement of the reactive oxygen species (ROS) …
However, achieving the synergistic enhancement of the reactive oxygen species (ROS) …
Multifunctional iron-apigenin nanocomplex conducting photothermal therapy and triggering augmented immune response for triple negative breast cancer
R Chen, Z Jiang, Y Cheng, J Ye, S Li, Y Xu, Z Ye… - International journal of …, 2024 - Elsevier
Triple negative breast cancer (TNBC) presents a formidable challenge due to its low
sensitivity to many chemotherapeutic drugs and a relatively low overall survival rate in …
sensitivity to many chemotherapeutic drugs and a relatively low overall survival rate in …
Lutetium texaphyrin: A photocatalyst that triggers pyroptosis via biomolecular photoredox catalysis
Y Xu, CV Chau, J Lee, AC Sedgwick… - Proceedings of the …, 2024 - National Acad Sciences
Photon-controlled pyroptosis activation (PhotoPyro) is a promising technique for cancer
immunotherapy due to its noninvasive nature, precise control, and ease of operation. Here …
immunotherapy due to its noninvasive nature, precise control, and ease of operation. Here …
GSH-Responsive Liposomes with Heat Shock Protein Regulatory Ability for Efficient Photodynamic/Photothermal Combined Therapy of Tumors
H Deng, X Li, L Pan, M Tang, B Wang… - … Applied Materials & …, 2024 - ACS Publications
Phototherapy, represented by photodynamic therapy (PDT) and photothermal therapy (PTT),
has great potential in tumor treatment. However, the presence of antioxidant glutathione …
has great potential in tumor treatment. However, the presence of antioxidant glutathione …
Ferroptosis and cuproptosis: Metal-dependent cell death pathways activated in response to classical chemotherapy–Significance for cancer treatment?
M Kciuk, A Gielecińska, Ż Kałuzińska-Kołat… - … et Biophysica Acta (BBA …, 2024 - Elsevier
Apoptosis has traditionally been regarded as the desired cell death pathway activated by
chemotherapeutic drugs due to its controlled and non-inflammatory nature. However, recent …
chemotherapeutic drugs due to its controlled and non-inflammatory nature. However, recent …