Hypertension is the single most important modifiable risk factor for adult stroke. Stroke
mortality has significantly decreased over the last 5 decades; this decline has been mainly …

Pituitary adenomas (PAs) have been shown to cause excess cardiovascular disease
comorbidity and mortality. Cerebrovascular disease (CeVD) is a small subset of …

Dehydroepiandrosterone (DHEA) sulfotransferase, known as SULT2A1, converts the
androgen precursor DHEA to its inactive sulfate ester, DHEAS, thereby preventing the …

Context: Hypertension (HTN) has been reported in up to 60% of children with Cushing
syndrome (CS), but its course, side effects, and potential differences among various causes …

The prevalence of hypertension in children is increasing but its neurological effects are
under-recognised. Here, we describe acute and chronic effects of childhood hypertension …

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Objective To evaluate the association between Cushing syndrome and hypercoagulability in
children. Study design A prospective, observational study was performed of 54 patients with …

We report a 6-year-old girl with ACTH-independent Cushing syndrome secondary to
bilateral adrenal hyperplasia; she presented with hypertension and seizures, and magnetic …

Cerebrovascular disease (stroke) is one of the ten leading causes of death in children and
adolescents. Multiple etiologies, from arteriopathies to prothrombic states, can cause stroke …

Pituitary corticotroph adenomas (causing Cushing disease, CD) are the most common
cause of endogenous Cushing syndrome (CS) in children although their prevalence varies …