Arterial hypertension in women: state of the art and knowledge gaps
Hypertension is the leading risk factor for cardiovascular disease and premature death
among women globally. However, there is a fundamental lack of knowledge regarding the …
among women globally. However, there is a fundamental lack of knowledge regarding the …
Renin-angiotensin system and sex differences in COVID-19: a critical assessment
MC Chappell - Circulation Research, 2023 - Am Heart Assoc
The current epidemic of corona virus disease (COVID-19) has resulted in an immense
health burden that became the third leading cause of death and potentially contributed to a …
health burden that became the third leading cause of death and potentially contributed to a …
The renin angiotensin system as a therapeutic target in traumatic brain injury
S Villapol, ZC Janatpour, KO Affram, AJ Symes - Neurotherapeutics, 2023 - Elsevier
Traumatic brain injury (TBI) is a major public health problem, with limited pharmacological
options available beyond symptomatic relief. The renin angiotensin system (RAS) is …
options available beyond symptomatic relief. The renin angiotensin system (RAS) is …
Alternative renin-angiotensin system
M Bader, UM Steckelings, N Alenina, RAS Santos… - …, 2024 - Am Heart Assoc
The renin-angiotensin system is the most important peptide hormone system in the
regulation of cardiovascular homeostasis. Its classical arm consists of the enzymes, renin …
regulation of cardiovascular homeostasis. Its classical arm consists of the enzymes, renin …
Effects of the oral angiotensin II type 2 receptor agonist C21 in sugen-hypoxia induced pulmonary hypertension in rats
G Tornling, R Batta, D Salvail, J Raud… - International Journal of …, 2023 - mdpi.com
Substantial evidence supports the involvement of the renin-angiotensin system in pulmonary
hypertension (PH), and the angiotensin II type 2 receptor (AT2R) is known to exert tissue …
hypertension (PH), and the angiotensin II type 2 receptor (AT2R) is known to exert tissue …
Angiotensin II type 2 receptor activation preserves megalin in the kidney and prevents proteinuria in high salt diet fed rats
Proteinuria is a risk factor for and consequence of kidney injury. Angiotensin II type 2
receptor (AT2R) is an emerging reno-protective target and is anti-proteinuric under …
receptor (AT2R) is an emerging reno-protective target and is anti-proteinuric under …
Recent advances in understanding the molecular pathophysiology of angiotensin II receptors; Lessons from cell-selective receptor deletion in mice
The renin-angiotensin system (RAS) is an essential hormonal system involved in water and
sodium reabsorption, renal blood flow regulation, and arterial constriction. Systemic …
sodium reabsorption, renal blood flow regulation, and arterial constriction. Systemic …
The renin-angiotensin-aldosterone system (RAAS) signaling pathways and cancer: foes versus allies
The renin-angiotensin-aldosterone system (RAAS), is an old system with new fundamental
roles in cancer biology which influences cell growth, migration, death, and metastasis. RAAS …
roles in cancer biology which influences cell growth, migration, death, and metastasis. RAAS …
[PDF][PDF] Sequence-directed concentration of G protein-coupled receptors in COPII vesicles
G protein-coupled receptors (GPCRs) constitute the largest superfamily of plasma
membrane signaling proteins. However, virtually nothing is known about their recruitment to …
membrane signaling proteins. However, virtually nothing is known about their recruitment to …
An egg white-derived peptide enhances systemic insulin sensitivity and modulates markers of non-alcoholic fatty liver disease in obese, insulin resistant mice
SC de Campos Zani, R Wang, H Veida-Silva… - Metabolites, 2023 - mdpi.com
Non-alcoholic fatty liver disease (NAFLD), the hepatic manifestation of the metabolic
syndrome, is a global health problem. Currently, no pharmacological treatment is approved …
syndrome, is a global health problem. Currently, no pharmacological treatment is approved …