Differences in regional brain structure in toddlers with autism are related to future language outcomes
Abstract Language and social symptoms improve with age in some autistic toddlers, but not
in others, and such outcome differences are not clearly predictable from clinical scores …
in others, and such outcome differences are not clearly predictable from clinical scores …
Beneficial effects and neurobiological aspects of environmental enrichment associated to major depressive disorder and autism spectrum disorder
LM Manosso, LDR Broseghini, JMB Campos… - Brain Research …, 2022 - Elsevier
A suitable enriched environment favors development but can also influence behavior and
neuronal circuits throughout development. Studies have shown that environmental …
neuronal circuits throughout development. Studies have shown that environmental …
Modulation of PI3K/Akt/GSK3β signaling cascade through G protein-coupled receptor 55 (GPR55) activation: prenatal lysophosphatidylinositol attenuates valproic …
Abstract Aims Dysregulation of PI3K/Akt/GSK3β signaling has been implicated in various
neurological disorders, including autism spectrum disorder (ASD). G protein-coupled …
neurological disorders, including autism spectrum disorder (ASD). G protein-coupled …
Unlocking new avenues for neuropsychiatric disease therapy: the emerging potential of Peroxisome proliferator-activated receptors as promising therapeutic targets
Rationale Peroxisome proliferator-activated receptors (PPARs) are transcription factors that
regulate various physiological processes such as inflammation, lipid metabolism, and …
regulate various physiological processes such as inflammation, lipid metabolism, and …
Axin2 coupled excessive Wnt‐glycolysis signaling mediates social defect in autism spectrum disorders
M Wang, P Xian, W Zheng, Z Li, A Chen… - EMBO Molecular …, 2023 - embopress.org
Social dysfunction is the core syndrome of autism spectrum disorder (ASD) and lacks
effective medicine. Although numerous risk genes and relevant environmental factors have …
effective medicine. Although numerous risk genes and relevant environmental factors have …
[HTML][HTML] Determination of molecular signatures and pathways common to brain tissues of autism spectrum disorder: insights from comprehensive bioinformatics …
Autism spectrum disorder (ASD) is a collection of neurological disabilities marked by
difficulties with behavior, speech, language, and interaction. It is a complicated and …
difficulties with behavior, speech, language, and interaction. It is a complicated and …
A bibliometrics analysis and visualization of autism spectrum disorder
P Rong, Q Fu, X Zhang, H Liu, S Zhao, X Song… - Frontiers in …, 2022 - frontiersin.org
Background The prevalence of autism spectrum disorder (ASD) increased rapidly in the last
20 years. Although related research has developed rapidly, little is known about its etiology …
20 years. Although related research has developed rapidly, little is known about its etiology …
Fucoxanthin mitigates valproic acid-induced autistic behavior through modulation of the AKT/GSK-3β signaling pathway
P Anand, A Kaur, S Singh - European Journal of Pharmacology, 2024 - Elsevier
This study aimed to investigate the effects of fucoxanthin, a natural compound found in
seaweed, on various aspects of autism using a rat model induced by valproic acid (VPA) …
seaweed, on various aspects of autism using a rat model induced by valproic acid (VPA) …
Illuminating links between cis-regulators and trans-acting variants in the human prefrontal cortex
Background Neuropsychiatric disorders afflict a large portion of the global population and
constitute a significant source of disability worldwide. Although Genome-wide Association …
constitute a significant source of disability worldwide. Although Genome-wide Association …
Retinoic acid administration normalizes aberrant microglial activation via regulating TREM2 transcription in the PFC of valproic acid induced autism rat
L Luo, T Li, Q Wu, B Yuan, C Hu, T Yang, H Wei… - Neuroscience …, 2023 - Elsevier
Autism spectrum disorder (ASD) is a complex neurodevelopmental disease with an unclear
underlying pathogenesis. Disruption of retinoic acid (RA)-retinoic acid receptor α (RARα) …
underlying pathogenesis. Disruption of retinoic acid (RA)-retinoic acid receptor α (RARα) …