In vitro culture of sheep early-antral follicles: Milestones, challenges and future perspectives

M Ebrahimi, M Dattena, AM Luciano, S Succu… - Theriogenology, 2023 - Elsevier
Early antral follicles (EAFs) represent the transitional stage between pre-antral and antral
follicles, containing oocytes that have completed most of their growth phase. Therefore, they …

The intrafollicular concentration of leptin as a potential biomarker to predict oocyte maturity in in-vitro fertilization

KJ Hong, JJ Lin, LH Lin, TH Lai - Scientific Reports, 2022 - nature.com
Oocyte maturity is critical to the development potential of the embryo and pregnancy
outcomes in natural and in-vitro fertilization (IVF). In IVF, oocyte maturity is typically …

Presence of leptin and its receptor in the ram reproductive system and in vitro effect of leptin on sperm quality

Y Gao, G Zhao, Y Song, A Haire, A Yang, X Zhao… - PeerJ, 2022 - peerj.com
Leptin is a 16 kDa hormone encoded by obese (OB) gene in adipocytes. This molecule not
only regulates energy metabolism but also plays a role in the reproduction of mammals …

Estratégias para a melhoria da eficiência do cultivo folicular in vitro: Importância da suplementação do meio e estudo das alterações epigenéticas

AFB da Silva, LF de Lima… - Research, Society and …, 2021 - rsdjournal.org
The oxidative stress (OS) and epigenetic changes can impact folliculogenesis in different
species. In vitro culture (IVC) of follicles efficiently will require a better understanding of …

Leptin decreases apoptosis and promotes the activation of primordial follicles through the phosphatidylinositol-3-kinase/protein kinase B pathway in cultured ovine …

TJS Macedo, VG Menezes, RS Barberino, RLS Silva… - Zygote, 2021 - cambridge.org
This study evaluated the effects of leptin on primordial follicle survival and activation after in
vitro culture of ovine ovarian tissue and if leptin acts through the phosphatidylinositol-3 …

Effect of reduced water intake on ovarian reserve, leptin immunoexpression and impact of leptin on the in vitro culture of sheep secondary follicles

VG Menezes, APO do Monte… - Animal Reproduction …, 2023 - Elsevier
This study evaluated the effect of reduced water intake on survival, apoptosis and
immunoexpression of leptin in sheep preantral follicles, activation of primordial follicles …

Leptin alleviated ovarian ischemia-reperfusion injury in rats via modulation of Sirt-1/Nrf2 and TLR4/NF-kB/caspase-3 signaling pathways

HA Abdel-Hamid, NMRA Maqsoud, NDM Toni… - Endocrine …, 2023 - sciendo.com
Objective. Ovarian torsion is a gynecological emergency that occurs mostly during the
female reproductive years due to ovarian masses or surgical manipulation. This work aims …

[HTML][HTML] 瘦素对人脑血管平滑肌细胞活性及ROS 表达的影响

李阳阳, 王晓雪, 张峰菊, 许宏侠, 刘欣欣 - 2020 - jms.qdu.edu.cn
目的探讨瘦素对人脑血管平滑肌细胞(HBVSMCs) 活性及活性氧(ROS) 表达水平的影响.
方法体外培养HBVSMCs, 使用不同浓度瘦素干预HBVSMCs, 采用CCK-8 …