The pyroptotic role of Caspase-3/GSDME signalling pathway among various cancer: A Review

AA Bhat, R Thapa, O Afzal, N Agrawal… - International journal of …, 2023 - Elsevier
Cytotoxic drugs have long been recognised to kill cancer cells through apoptosis. According
to a current study, pyroptosis inhibits cell proliferation and shrinks tumors. Pyroptosis and …

Chlorogenic acid for cancer prevention and therapy: Current status on efficacy and mechanisms of action

A Gupta, AG Atanasov, Y Li, N Kumar… - Pharmacological …, 2022 - Elsevier
Chlorogenic acid (CA), also known as 5-O-caffeoylquinic acid, is a dietary phenolic acid
produced by various plant species. CA, is the most ubiquitous compound among the …

New horizons in lung cancer management through ATR/CHK1 pathway modulation

R Thapa, O Afzal, AA Bhat, A Goyal… - Future medicinal …, 2023 - Future Science
Lung cancer is the leading cause of cancer-related deaths worldwide. Molecular profiling
has contributed to a new classification of lung cancer, driving advancements in research and …

From LncRNA to metastasis: The MALAT1-EMT axis in cancer progression

R Thapa, O Afzal, M Afzal, G Gupta, AA Bhat… - … -Research and Practice, 2023 - Elsevier
Cancer is a complex disease that causes abnormal genetic changes and unchecked cellular
growth. It also causes a disruption in the normal regulatory processes that leads to the …

Application analysis of ai technology combined with spiral CT scanning in early lung cancer screening

S Li, L Yu, B Liu, Q Lin, J Huang - arXiv preprint arXiv:2402.04267, 2024 - arxiv.org
At present, the incidence and fatality rate of lung cancer in China rank first among all
malignant tumors. Despite the continuous development and improvement of China's medical …

Association of lung-intestinal microecology and lung cancer therapy

LY Kong, XY Chen, X Lu, Q Caiyin, DH Yang - Chinese Medicine, 2023 - Springer
In recent years, the incidence of lung cancer is increasing. Lung cancer has become one of
the most malignant tumors with the highest incidence in the world, which seriously affects …

Prognostic factors in advanced non-small cell lung cancer patients treated with immunotherapy

D Rocco, L Della Gravara, A Ragone, L Sapio… - Cancers, 2023 - mdpi.com
Simple Summary Immunotherapy in the form of Immune Checkpoint Inhibitors which
currently represent one of the staples of advanced Non-Small Cell Lung Cancer treatment …

Exosome nanovesicles as potential biomarkers and immune checkpoint signaling modulators in lung cancer microenvironment: recent advances and emerging …

NA Khan, M Asim, KH Biswas, AN Alansari… - Journal of Experimental …, 2023 - Springer
Lung cancer remains the leading cause of cancer-related deaths globally, and the survival
rate remains low despite advances in diagnosis and treatment. The progression of lung …

T lymphocyte cell: a pivotal player in lung cancer

Y Wu, M Yuan, C Wang, Y Chen, Y Zhang… - Frontiers in …, 2023 - frontiersin.org
Lung cancer is responsible for the leading cause of cancer-related death worldwide, which
lacks effective therapies. In recent years, accumulating evidence on the understanding of the …

Treatment of advanced non-small cell lung cancer with RET fusions: reality and hopes

D Rocco, L Sapio, L Della Gravara, S Naviglio… - International Journal of …, 2023 - mdpi.com
RET-selective tyrosine kinase inhibitors (TKIs) selpercatinib and pralsetinib have
revolutionized the landscape of RET-positive (RET+) advanced non-small cell lung cancer …