Patient communication and experiences in cancer clinical drug trials: a mixed-method study at a specialist clinical trials unit

R Forbes Shepherd, A Bradford, M Lieschke… - Trials, 2023 - Springer
Background As cancer therapies increase in their complexity, effective communication
among patients, physicians, and research staff is critical for optimal clinical trial …

Palliative care integration for patients on phase I cancer clinical trials

ACR Uhelski, M Wheless, EJ Davis… - Current Problems in …, 2023 - Elsevier
Early integration of palliative care (PC) is recommended as standard of care for patients with
advanced cancer. However, challenges remain for both medical oncologists and PC …

Understanding barriers and facilitators to palliative and end-of-life care research: a mixed method study of generalist and specialist health, social care, and research …

C Walshe, L Dunleavy, N Preston, S Payne… - BMC Palliative Care, 2024 - Springer
Background Palliative care provision should be driven by high quality research evidence.
However, there are barriers to conducting research. Most research attention focuses on …

When research becomes practice: the concept of the therapeutic misconception and challenges to consent in clinical trials

S Heynemann, W Lipworth… - Internal Medicine …, 2023 - Wiley Online Library
Many factors influence patients' decisions to participate in clinical trials. For many, the
primary motivation is the possibility that they might derive some benefit from participation …

Decision-making and autonomy among participants in early-phase cancer immunotherapy trials: a qualitative study

J Avery, JAH Bell, K Baryolay, G Rodin, R Nissim… - BMC cancer, 2024 - Springer
Background Participants considering early-phase cancer clinical trials (CTs) need to
understand the unique risks and benefits prior to providing informed consent. This …

What matters most to people with metastatic uveal melanoma? A qualitative study to inform future measurement of health-related quality of life

CA Ng, T Luckett, B Mulhern, D Kee… - Melanoma …, 2024 - journals.lww.com
Metastatic uveal melanoma (mUM) is a rare cancer with poor prognosis, but novel
treatments are emerging. Currently, there are no mUM-specific health-related quality of life …

Identifying locally actionable strategies to increase participant acceptability and feasibility to participate in Phase I cancer clinical trials

SAS Staras, EN Wollney, LE Emerson… - Health …, 2024 - Wiley Online Library
Background Recruitment of cancer clinical trial (CCT) participants, especially participants
representing the diversity of the US population, is necessary to create successful …

“There was No Opportunity to Express Good or Bad”: Perspectives From Patient Focus Groups on Patient Experience in Clinical Trials

P Boyd, EA Sternke, DJ Tite… - Journal of Patient …, 2024 - journals.sagepub.com
To understand how patients perceive their experiences leading up to, during, and after a
clinical trial, and the relationship these experiences had with future willingness to …

Implementing an educational resource for patients participating in cancer clinical trials during the pandemic

B Hood, T Finch - British Journal of Nursing, 2024 - magonlinelibrary.com
This research is centred in the specialty of early phase cancer research–the branch of
clinical research that focuses on phase one and phase two clinical trials. The aim was to …

Development of a Japanese Scale that Evaluates the Level of Nursing Support Provided to Patients for Decision-Making in Cancer Clinical Trials

I Kohara, N Fujiwara, S Tamaki, H Nakahama… - Journal of Cancer …, 2023 - Springer
Clinical nurses need learning programs that are useful in nursing support for patients'
decision-making (NSPDM) regarding cancer clinical trials (CCTs). The usefulness of the …