ST-segment elevation myocardial infarction (STEMI) is the most acute manifestation of
coronary artery disease and is associated with great morbidity and mortality. A complete …

Diseases of the cardiovascular system are the leading cause of morbidity and mortality in
men and women in developed countries, and cardiovascular disease (CVD) is becoming …

Abstract Treatment with therapy targeting BRAF and MEK (BRAF/MEK) has revolutionized
care in melanoma and other cancers; however, therapeutic resistance is common and …

Migraine is a major neurological disorder affecting one in nine adults worldwide with a
significant impact on health care and socioeconomic systems. Migraine is more prevalent in …

Sex differences between males and females can be detected early in life. They are present
also later even to a much greater extent affecting our life in adulthood and a wide spectrum …

We address two aims: Aim 1 (Fitness Review) compares the effect of higher
cardiorespiratory fitness (CRF)(eg, endurance athletes) with lower CRF (eg, sedentary …

The convergence of tissue engineering and patient-specific stem cell biology has enabled
the engineering of in vitro tissue models that allow the study of patient-tailored treatment …

Sex hormone receptors are expressed throughout the vasculature and play an important
role in the modulation of blood pressure in health and disease. The functions of these …

Concerns regarding sex differences are increasingly pertinent in scientific and societal
arenas. Although biological sex and socio-cultural gender are increasingly recognized as …

Dementia is a neurocognitive disorder characterized by a progressive memory loss and
impairment in cognitive and functional abilities. Autophagy and mitophagy are two important …