MyD88, a key adaptor molecule required for many innate immunity receptor-activated
signaling pathways, was evaluated in a Chlamydia muridarum urogenital tract infection …

The failure of the inactivated Chlamydia-based vaccine trials in the 1960s has led
researchers studying Chlamydia to take cautious and rational approaches to develop safe …

Plasmid-free Chlamydia trachomatis and Chlamydia muridarum fail to induce severe
pathology. To evaluate whether the attenuated pathogenicity is due to insufficient infection …

The female lower genital tract is constantly exposed to microbial infection, some of which
can ascend to and cause pathology such as hydrosalpinx in the upper genital tract, which …

Chlamydia trachomatis infection induces a wide array of inflammatory cytokines and
chemokines, which may contribute to chlamydia-induced pathologies. However, the precise …

The chlamydial inclusion membrane is extensively modified by the insertion of type III
secreted effector proteins. These inclusion membrane proteins (Incs) are exposed to the …

Chlamydia trachomatis is the leading cause of infectious blindness and a sexually
transmitted infection. All chlamydiae are obligate intracellular bacteria that replicate within a …

Infection with Chlamydia trachomatis induces inflammatory pathologies in the urogenital
tract that can lead to infertility and ectopic pregnancy. Pathogenesis of infection has been …

Lower genital tract infection with Chlamydia trachomatis and C. muridarum can induce long-
lasting hydrosalpinx in the upper genital tract of women and female mice, respectively …

Glycogen has been localized both inside and outside Chlamydia trachomatis organisms. We
now report that C. trachomatis glycogen synthase (GlgA) was detected in both chlamydial …