[HTML][HTML] New-age vaccine adjuvants, their development, and future perspective

SK Verma, P Mahajan, NK Singh, A Gupta… - Frontiers in …, 2023 - frontiersin.org
In the present scenario, immunization is of utmost importance as it keeps us safe and
protects us from infectious agents. Despite the great success in the field of vaccinology …

Advances in SARS-CoV-2 receptor-binding domain-based COVID-19 vaccines

X Guan, Y Yang, L Du - Expert review of vaccines, 2023 - Taylor & Francis
ABSTRACT Introduction The Coronavirus Disease 2019 (COVID-19) pandemic has caused
devastating human and economic costs. Vaccination is an important step in controlling the …

[HTML][HTML] Cross-reactivity and sequence similarity between microbial transglutaminase and human tissue antigens

A Lerner, C Benzvi, A Vojdani - Scientific Reports, 2023 - nature.com
Microbial transglutaminase (mTG) is a bacterial survival factor, frequently used as a food
additive to glue processed nutrients. As a result, new immunogenic epitopes are generated …

Colloidal polyelectrolyte complexes from hyaluronic acid: Preparation and biomedical applications

HV Le, D Le Cerf - Small, 2022 - Wiley Online Library
Hyaluronic acid (HA) is a naturally occurring polysaccharide which has been extensively
exploited in biomedical fields owing to its outstanding biocompatibility. Self‐assembly of HA …

Whole tumour cell-based vaccines: tuning the instruments to orchestrate an optimal antitumour immune response

A Pérez-Baños, MA Gleisner, I Flores, C Pereda… - British Journal of …, 2023 - nature.com
Immunotherapy, particularly those based on immune checkpoint inhibitors (ICIs), has
become a useful approach for many neoplastic diseases. Despite the improvements of ICIs …

Injectable Hydrogel Mucosal Vaccine Elicits Protective Immunity against Respiratory Viruses

W Fu, M Guo, X Zhou, Z Wang, J Sun, Y An, T Guan… - ACS …, 2024 - ACS Publications
Intranasal vaccines, eliciting mucosal immune responses, can prevent early invasion,
replication, and transmission of pathogens in the respiratory tract. However, the effective …

Microbial exopolysaccharides–β-glucans–as promising postbiotic candidates in vaccine adjuvants

A Abbasi, TR Saadat, YR Saadat - International Journal of Biological …, 2022 - Elsevier
The urgent task of creating new, enhanced adjuvants is closely related to our
comprehension of their mechanisms of action. A few adjuvants have shown sufficient …

Recent advances in respiratory immunization: A focus on COVID-19 vaccines

X He, X Chen, H Wang, G Du, X Sun - Journal of Controlled Release, 2023 - Elsevier
The development of vaccines has always been an essential task worldwide since vaccines
are regarded as powerful weapons in protecting the global population. Although the vast …

[HTML][HTML] The next-generation DNA vaccine platforms and delivery systems: Advances, challenges and prospects

B Lu, JM Lim, B Yu, S Song, P Neeli… - Frontiers in …, 2024 - frontiersin.org
Vaccines have proven effective in the treatment and prevention of numerous diseases.
However, traditional attenuated and inactivated vaccines suffer from certain drawbacks such …

[HTML][HTML] Principles and therapeutic applications of adaptive immunity

H Chi, M Pepper, PG Thomas - Cell, 2024 - cell.com
Adaptive immunity provides protection against infectious and malignant diseases. These
effects are mediated by lymphocytes that sense and respond with targeted precision to …