The relationship between interleukin‐1 receptor antagonist and cognitive function in older adults with bipolar disorder

FE Lotrich, MA Butters, H Aizenstein… - … Journal of Geriatric …, 2014 - Wiley Online Library
Objective Cognitive impairments are a feature of bipolar disorder (BD) and could be
worsened by inflammatory cytokines. We determined whether (i) serum interleukin‐1 …

Characterization of the early neuroinflammation after spinal cord injury in mice

T Rice, J Larsen, S Rivest… - Journal of Neuropathology …, 2007 - academic.oup.com
The occurrence of neuroinflammation after spinal cord injury (SCI) is well established, but its
function is debated, with both beneficial and detrimental consequences ascribed. A …

Mending the broken brain: neuroimmune interactions in neurogenesis

E Molina‐Holgado… - Journal of …, 2010 - Wiley Online Library
J. Neurochem.(2010) 114, 1277–1290. Abstract Neuroimmune networks and the brain
endocannabinoid system contribute to the maintenance of neurogenesis. Cytokines and …

β− Amyloid exacerbates inflammation in astrocytes lacking fatty acid amide hydrolase through a mechanism involving PPAR‐α, PPAR‐γ and TRPV1, but not CB1 or …

C Benito, RM Tolón, AI Castillo… - British journal of …, 2012 - Wiley Online Library
BACKGROUND AND PURPOSE The endocannabinoid system may regulate glial cell
functions and their responses to pathological stimuli, specifically, Alzheimer's disease. One …

Modeling intracerebal hemorrhage: glutamate, nuclear factor-κB signaling and cytokines

KR Wagner - Stroke, 2007 - Am Heart Assoc
A significant amount of new information has been generated in animal models of
intracerebral hemorrhage during the past several years. These include findings on the …

[PDF][PDF] Pathophysiology of neurodegeneration following traumatic brain injury.

MAM Freire - West Indian Medical Journal, 2012 - researchgate.net
Acute neuropathological conditions, including brain and spinal cord trauma, are leading
causes of death and disabilities worldwide, especially in children and young adults. The …

It may take inflammation, phosphorylation and ubiquitination to 'tangle'in Alzheimer's disease

L Arnaud, NK Robakis… - Neurodegenerative …, 2007 - karger.com
Neurofibrillary tangles (NFT) are one of the pathologic hallmarks of Alzheimer's disease
(AD). Their major component is tau, a protein that becomes hyperphosphorylated and …

COG1410, a novel apolipoprotein E–based peptide, improves functional recovery in a murine model of traumatic brain injury

DT Laskowitz, SE McKenna, P Song, H Wang… - Journal of …, 2007 - liebertpub.com
Traumatic brain injury (TBI) is a silent epidemic affecting approximately 1.4 million
Americans annually, at an estimated annual cost of $60 billion in the United States alone …

Role of the cell cycle in the pathobiology of central nervous system trauma

I Cernak, BA Stoica, KR Byrnes, SD Giovanni, AI Faden - Cell cycle, 2005 - Taylor & Francis
Up-regulation of cell cycle proteins occurs in both mitotic and post-mitotic neural cells after
central nervous system (CNS) injury in adult animals. In mitotic cells, such as astroglia and …

[HTML][HTML] Intermittent lead exposure induces behavioral and cardiovascular alterations associated with neuroinflammation

L Shvachiy, Â Amaro-Leal, TF Outeiro, I Rocha… - Cells, 2023 - mdpi.com
The nervous system is the primary target for lead exposure and the developing brain
appears to be especially susceptible, namely the hippocampus. The mechanisms of lead …