Detecting polygenic evolution: problems, pitfalls, and promises
M Wellenreuther, B Hansson - TRENDS in Genetics, 2016 - cell.com
Unraveling the genetic basis of organismal form and function remains one of the major goals
of evolutionary biology. Theory has long supported a model of polygenic evolution in which …
of evolutionary biology. Theory has long supported a model of polygenic evolution in which …
The QTN program and the alleles that matter for evolution: all that's gold does not glitter
MV Rockman - Evolution, 2012 - academic.oup.com
The search for the alleles that matter, the quantitative trait nucleotides (QTNs) that underlie
heritable variation within populations and divergence among them, is a popular pursuit. But …
heritable variation within populations and divergence among them, is a popular pursuit. But …
Human adaptation over the past 40,000 years
I Mathieson - Current opinion in genetics & development, 2020 - Elsevier
Over the past few years several methodological and data-driven advances have greatly
improved our ability to robustly detect genomic signatures of selection in humans. New …
improved our ability to robustly detect genomic signatures of selection in humans. New …
Integrated environmental and genomic analysis reveals the drivers of local adaptation in African indigenous chickens
AA Gheyas, A Vallejo-Trujillo, A Kebede… - Molecular biology …, 2021 - academic.oup.com
Breeding for climate resilience is currently an important goal for sustainable livestock
production. Local adaptations exhibited by indigenous livestock allow investigating the …
production. Local adaptations exhibited by indigenous livestock allow investigating the …
Catch me if you can: adaptation from standing genetic variation to a moving phenotypic optimum
Adaptation lies at the heart of Darwinian evolution. Accordingly, numerous studies have tried
to provide a formal framework for the description of the adaptive process. Of these, two …
to provide a formal framework for the description of the adaptive process. Of these, two …
Broad-scale variation in human genetic diversity levels is predicted by purifying selection on coding and non-coding elements
Analyses of genetic variation in many taxa have established that neutral genetic diversity is
shaped by natural selection at linked sites. Whether the mode of selection is primarily the …
shaped by natural selection at linked sites. Whether the mode of selection is primarily the …
Fisher's geometric model with a moving optimum
Fisher's geometric model has been widely used to study the effects of pleiotropy and
organismic complexity on phenotypic adaptation. Here, we study a version of Fisher's model …
organismic complexity on phenotypic adaptation. Here, we study a version of Fisher's model …
A Variable Genetic Architecture of Melanic Evolution in Drosophila melanogaster
Unraveling the genetic architecture of adaptive phenotypic divergence is a fundamental
quest in evolutionary biology. In Drosophila melanogaster, high-altitude melanism has …
quest in evolutionary biology. In Drosophila melanogaster, high-altitude melanism has …
A theory of oligogenic adaptation of a quantitative trait
I Höllinger, B Wölfl, J Hermisson - Genetics, 2023 - academic.oup.com
Rapid phenotypic adaptation is widespread in nature, but the underlying genetic dynamics
remain controversial. Whereas population genetics envisages sequential beneficial …
remain controversial. Whereas population genetics envisages sequential beneficial …
[PDF][PDF] Chasing the mechanisms of ecologically adaptive salinity tolerance
Plants adapted to challenging environments offer fascinating models of evolutionary
change. Importantly, they also give information to meet our pressing need to develop …
change. Importantly, they also give information to meet our pressing need to develop …