[HTML][HTML] Impaired development of neocortical circuits contributes to the neurological alterations in DYRK1A haploinsufficiency syndrome

J Arranz, E Balducci, K Arató, G Sánchez-Elexpuru… - Neurobiology of …, 2019 - Elsevier
Autism spectrum disorders are early onset neurodevelopmental disorders characterized by
deficits in social communication and restricted repetitive behaviors, yet they are quite …

Combining aperiodic 1/f slopes and brain simulation: An EEG/MEG proxy marker of excitation/inhibition imbalance in Alzheimer's disease

P Martínez‐Cañada, E Perez‐Valero… - Alzheimer's & …, 2023 - Wiley Online Library
INTRODUCTION Accumulation and interaction of amyloid‐beta (Aβ) and tau proteins during
progression of Alzheimer's disease (AD) are shown to tilt neuronal circuits away from …

Cell-type-specific synaptic imbalance and disrupted homeostatic plasticity in cortical circuits of ASD-associated Chd8 haploinsufficient mice

RA Ellingford, MJ Panasiuk, ER de Meritens… - Molecular …, 2021 - nature.com
Heterozygous mutation of chromodomain helicase DNA binding protein 8 (CHD8) is strongly
associated with autism spectrum disorder (ASD) and results in dysregulated expression of …

Oxytocin impacts top-down and bottom-up social perception in adolescents with ASD: a MEG study of neural connectivity

A Korisky, I Gordon, A Goldstein - Molecular Autism, 2022 - Springer
Background In the last decade, accumulative evidence has shown that oxytocin can
modulate social perception in typically developed individuals and individuals diagnosed …

GABA Neuronal Deletion of Shank3 Exons 14–16 in Mice Suppresses Striatal Excitatory Synaptic Input and Induces Social and Locomotor Abnormalities

T Yoo, H Cho, J Lee, H Park, YE Yoo… - Frontiers in cellular …, 2018 - frontiersin.org
Shank3 is an excitatory postsynaptic scaffolding protein implicated in multiple brain
disorders, including autism spectrum disorders (ASD) and Phelan-McDermid syndrome …

Shank3 Exons 14–16 Deletion in Glutamatergic Neurons Leads to Social and Repetitive Behavioral Deficits Associated With Increased Cortical Layer 2/3 Neuronal …

T Yoo, H Cho, H Park, J Lee, E Kim - Frontiers in cellular …, 2019 - frontiersin.org
Shank3, an abundant excitatory postsynaptic scaffolding protein, has been associated with
multiple brain disorders, including autism spectrum disorders (ASD) and Phelan-McDermid …

Early and late corrections in mouse models of autism spectrum disorder

C Chung, W Shin, E Kim - Biological Psychiatry, 2022 - Elsevier
Autism spectrum disorder (ASD) is a neurodevelopmental disorder characterized by social
and repetitive symptoms. A key feature of ASD is early-life manifestations of symptoms …

Chronic exposure to environmentally relevant concentrations of carbamazepine interferes with anxiety response of adult female zebrafish through GABA/5-HT …

CT Xie, ML Tan, YW Li, QL Chen, YJ Shen… - … and Physiology Part C …, 2023 - Elsevier
Carbamazepine (CBZ) is one of the widely distributed pharmaceutical residues in aquatic
environments, yet few researches have addressed its chronic effect on the anxiety of fish …

Testing the excitation/inhibition imbalance hypothesis in a mouse model of the autism spectrum disorder: in vivo neurospectroscopy and molecular evidence for …

J Gonçalves, IR Violante, J Sereno, RA Leitão, Y Cai… - Molecular Autism, 2017 - Springer
Abstract Background Excitation/inhibition (E/I) imbalance remains a widely discussed
hypothesis in autism spectrum disorders (ASD). The presence of such an imbalance may …

The domestic chick as an animal model of autism spectrum disorder: building adaptive social perceptions through prenatally formed predispositions

T Matsushima, T Izumi, G Vallortigara - Frontiers in Neuroscience, 2024 - frontiersin.org
Equipped with an early social predisposition immediately post-birth, humans typically form
associations with mothers and other family members through exposure learning, canalized …