Major depressive disorder

W Marx, BWJH Penninx, M Solmi… - Nature Reviews …, 2023 - nature.com
Major depressive disorder (MDD) is characterized by persistent depressed mood, loss of
interest or pleasure in previously enjoyable activities, recurrent thoughts of death, and …

[HTML][HTML] Short chain fatty acids: microbial metabolites for gut-brain axis signalling

KJ O'Riordan, MK Collins, GM Moloney… - Molecular and Cellular …, 2022 - Elsevier
The role of the intestinal microbiota as a regulator of gut-brain axis signalling has risen to
prominence in recent years. Understanding the relationship between the gut microbiota, the …

[HTML][HTML] Microbiota medicine: towards clinical revolution

P Gebrayel, C Nicco, S Al Khodor, J Bilinski… - Journal of translational …, 2022 - Springer
The human gastrointestinal tract is inhabited by the largest microbial community within the
human body consisting of trillions of microbes called gut microbiota. The normal flora is the …

[HTML][HTML] Gut microbiota interact with the brain through systemic chronic inflammation: implications on neuroinflammation, neurodegeneration, and aging

Y Mou, Y Du, L Zhou, J Yue, X Hu, Y Liu… - Frontiers in …, 2022 - frontiersin.org
It has been noticed in recent years that the unfavorable effects of the gut microbiota could
exhaust host vigor and life, yet knowledge and theory are just beginning to be established …

Gut microbiome–brain alliance: a landscape view into mental and gastrointestinal health and disorders

JM Sasso, RM Ammar, R Tenchov… - ACS Chemical …, 2023 - ACS Publications
Gut microbiota includes a vast collection of microorganisms residing within the
gastrointestinal tract. It is broadly recognized that the gut and brain are in constant …

[HTML][HTML] The gut microbiome in depression and potential benefit of prebiotics, probiotics and synbiotics: a systematic review of clinical trials and observational studies

SR Alli, I Gorbovskaya, JCW Liu, NJ Kolla… - International journal of …, 2022 - mdpi.com
An emerging body of literature demonstrates differences in the gut microbiome (GMB) of
patients with major depressive disorder (MDD) compared to healthy controls (HC), as well …

[HTML][HTML] Probiotics for Alzheimer's disease: a systematic review

R Naomi, H Embong, F Othman, HF Ghazi, N Maruthey… - Nutrients, 2021 - mdpi.com
Alzheimer's disease (AD) is the most common form of neurodegenerative disorders affecting
mostly the elderly. It is characterized by the presence of Aβ and neurofibrillary tangles (NFT) …

[HTML][HTML] Microbiota alteration and modulation in Alzheimer's disease by gerobiotics: the gut-health axis for a good mind

D Ağagündüz, B Kocaadam-Bozkurt, O Bozkurt… - Biomedicine & …, 2022 - Elsevier
The role of the gut microbiota in human health is one of the most important research topics.
There is a strong relationship between the microbiota-gut-brain axis and cognitive functions …

[HTML][HTML] The gut microbiota–brain axis in neurological disorder

H Ullah, S Arbab, Y Tian, C Liu, Y Chen… - Frontiers in …, 2023 - frontiersin.org
The gut microbiota (GM) plays an important role in the physiology and pathology of the host.
Microbiota communicate with different organs of the organism by synthesizing hormones …

Inflammation, lifestyle factors, and the microbiome‐gut‐brain Axis: relevance to depression and antidepressant action

F Donoso, JF Cryan… - Clinical …, 2023 - Wiley Online Library
Depression is considered a major public health concern, where existing pharmacological
treatments are not equally effective across all patients. The pathogenesis of depression …