[HTML][HTML] Synaptic plasticity in the pain-related cingulate and insular cortex

JHA Lee, Q Chen, M Zhuo - Biomedicines, 2022 - mdpi.com
Cumulative animal and human studies have consistently demonstrated that two major
cortical regions in the brain, namely the anterior cingulate cortex (ACC) and insular cortex …

Cortical interneurons in autism

A Contractor, IM Ethell, C Portera-Cailliau - Nature neuroscience, 2021 - nature.com
The mechanistic underpinnings of autism remain a subject of debate and controversy. Why
do individuals with autism share an overlapping set of atypical behaviors and symptoms …

Intrinsic activity development unfolds along a sensorimotor–association cortical axis in youth

VJ Sydnor, B Larsen, J Seidlitz, A Adebimpe… - Nature …, 2023 - nature.com
Animal studies of neurodevelopment have shown that recordings of intrinsic cortical activity
evolve from synchronized and high amplitude to sparse and low amplitude as plasticity …

[HTML][HTML] Prenatal interleukin 6 elevation increases glutamatergic synapse density and disrupts hippocampal connectivity in offspring

F Mirabella, G Desiato, S Mancinelli, G Fossati… - Immunity, 2021 - cell.com
Early prenatal inflammatory conditions are thought to be a risk factor for different
neurodevelopmental disorders. Maternal interleukin-6 (IL-6) elevation during pregnancy …

[HTML][HTML] Topographic gradients of intrinsic dynamics across neocortex

G Shafiei, RD Markello, R Vos de Wael, BC Bernhardt… - elife, 2020 - elifesciences.org
The intrinsic dynamics of neuronal populations are shaped by both microscale attributes and
macroscale connectome architecture. Here we comprehensively characterize the rich …

[HTML][HTML] Increased fMRI connectivity upon chemogenetic inhibition of the mouse prefrontal cortex

F Rocchi, C Canella, S Noei… - Nature …, 2022 - nature.com
While shaped and constrained by axonal connections, fMRI-based functional connectivity
reorganizes in response to varying interareal input or pathological perturbations. However …

[HTML][HTML] Intrinsic excitation-inhibition imbalance affects medial prefrontal cortex differently in autistic men versus women

S Trakoshis, P Martínez-Cañada, F Rocchi, C Canella… - elife, 2020 - elifesciences.org
Excitation-inhibition (E: I) imbalance is theorized as an important pathophysiological
mechanism in autism. Autism affects males more frequently than females and sex-related …

[HTML][HTML] Brain mapping across 16 autism mouse models reveals a spectrum of functional connectivity subtypes

V Zerbi, M Pagani, M Markicevic, M Matteoli… - Molecular …, 2021 - nature.com
Abstract Autism Spectrum Disorder (ASD) is characterized by substantial, yet highly
heterogeneous abnormalities in functional brain connectivity. However, the origin and …

Cross-talk between GABAergic postsynapse and microglia regulate synapse loss after brain ischemia

T Cramer, R Gill, ZS Thirouin, M Vaas, S Sampath… - Science …, 2022 - science.org
Microglia interact with neurons to facilitate synapse plasticity; however, signal (s)
contributing to microglia activation for synapse elimination in pathology are not fully …

[HTML][HTML] Neurophysiological signatures of cortical micro-architecture

G Shafiei, BD Fulcher, B Voytek… - Nature …, 2023 - nature.com
Systematic spatial variation in micro-architecture is observed across the cortex. These micro-
architectural gradients are reflected in neural activity, which can be captured by …