Injectable hydrogels for cartilage and bone tissue engineering

M Liu, X Zeng, C Ma, H Yi, Z Ali, X Mou, S Li, Y Deng… - Bone research, 2017 - nature.com
Tissue engineering has become a promising strategy for repairing damaged cartilage and
bone tissue. Among the scaffolds for tissue-engineering applications, injectable hydrogels …

Drug delivery by supramolecular design

MJ Webber, R Langer - Chemical Society Reviews, 2017 - pubs.rsc.org
The rational design of drug delivery approaches leveraging supramolecular chemistry
(ie,“chemistry beyond the molecule”) has garnered significant interest in recent years toward …

Synthetic extracellular matrices with function-encoding peptides

C Ligorio, A Mata - Nature reviews bioengineering, 2023 - nature.com
The communication of cells with their surroundings is mostly encoded in the epitopes of
structural and signalling proteins present in the extracellular matrix (ECM). These peptide …

Peptide supramolecular materials for therapeutics

K Sato, MP Hendricks, LC Palmer… - Chemical Society Reviews, 2018 - pubs.rsc.org
Supramolecular assembly of peptide-based monomers into nanostructures offers many
promising applications in advanced therapies. In this Tutorial Review, we introduce …

Heparin-functionalized polymeric biomaterials in tissue engineering and drug delivery applications

Y Liang, KL Kiick - Acta biomaterialia, 2014 - Elsevier
Heparin plays an important role in many biological processes via its interaction with various
proteins, and hydrogels and nanoparticles comprising heparin exhibit attractive properties …

Biomaterial-driven in situ cardiovascular tissue engineering—a multi-disciplinary perspective

TB Wissing, V Bonito, CVC Bouten… - NPJ Regenerative …, 2017 - nature.com
There is a persistent and growing clinical need for readily-available substitutes for heart
valves and small-diameter blood vessels. In situ tissue engineering is emerging as a …

Photoactuating artificial muscles of motor amphiphiles as an extracellular matrix mimetic scaffold for mesenchymal stem cells

S Chen, L Yang, FKC Leung, T Kajitani… - Journal of the …, 2022 - ACS Publications
Mimicking the native extracellular matrix (ECM) as a cell culture scaffold has long attracted
scientists from the perspective of supramolecular chemistry for potential application in …

Protein-mimetic peptide nanofibers: Motif design, self-assembly synthesis, and sequence-specific biomedical applications

W Zhang, X Yu, Y Li, Z Su, KD Jandt, G Wei - Progress in Polymer Science, 2018 - Elsevier
The design and fabrication of self-assembled peptide nanostructures offer an amazing
platform for creating functional nanomaterials for various biomedical applications. Utilizing …

Hyaluronic acid biomaterials for central nervous system regenerative medicine

G Jensen, JL Holloway, SE Stabenfeldt - Cells, 2020 - mdpi.com
Hyaluronic acid (HA) is a primary component of the brain extracellular matrix and functions
through cellular receptors to regulate cell behavior within the central nervous system (CNS) …

Effect of sustained heparin release from PCL/chitosan hybrid small-diameter vascular grafts on anti-thrombogenic property and endothelialization

Y Yao, J Wang, Y Cui, R Xu, Z Wang, J Zhang, K Wang… - Acta biomaterialia, 2014 - Elsevier
Thrombus formation and subsequent occlusion are the main reasons for the failure of small-
diameter vascular grafts. In this study, a hybrid small-diameter vascular graft was developed …