Soluble N-ethylmaleimide-sensitive factor attachment protein receptors (SNAREs) are a
family of small conserved eukaryotic proteins that mediate membrane fusion between …

Biological membranes are dynamic heterogeneous materials, and their shape and
organization are tightly coupled to the properties of the proteins in and around them …

Molecular dynamics simulations of cellular membranes have come a long way—from simple
model lipid bilayers to multicomponent systems capturing the crowded and complex nature …

The Martini model is a popular force field for coarse-grained simulations. Membranes have
always been at the center of its development, with the latest version, Martini 3, showing great …

Abstract Synaptotagmin 7 (Syt-7) is part of the synaptotagmin protein family that regulates
exocytotic lipid membrane fusion. Among the family, Syt-7 stands out by its membrane …

In this chapter, we present a novel computational framework to study the dynamic behavior
of extensive membrane systems, potentially in interaction with peripheral proteins, as an …

Methodology for extracting the spontaneous curvature, bending modulus, and neutral
surface of a lipid bilayer is described. The" SPEX" method is a robust technique for …

All lipid membranes have inherent morphological preferences and resist deformation. Yet
adaptations in membrane shape can and do occur at multiple length scales. While this …

Cellular membranes harbor hundreds of lipid species and 30% of the proteins expressed in
mammalian cells. These molecules in the membrane can fulfill their functions individually …