Roles of JAK2 in aging, inflammation, hematopoiesis and malignant transformation
Clonal alterations in hematopoietic cells occur during aging and are often associated with
the establishment of a subclinical inflammatory environment. Several age-related conditions …
the establishment of a subclinical inflammatory environment. Several age-related conditions …
A Broad Overview of Signaling in Ph-Negative Classic Myeloproliferative Neoplasms
A Guijarro-Hernández, JL Vizmanos - Cancers, 2021 - mdpi.com
Simple Summary There is growing evidence that Ph-negative myeloproliferative neoplasms
are disorders in which multiple signaling pathways are significantly disturbed. The …
are disorders in which multiple signaling pathways are significantly disturbed. The …
A randomized double-blind trial of 3 aspirin regimens to optimize antiplatelet therapy in essential thrombocythemia
Essential thrombocythemia (ET) is characterized by abnormal megakaryopoiesis and
enhanced thrombotic risk. Once-daily low-dose aspirin is the recommended antithrombotic …
enhanced thrombotic risk. Once-daily low-dose aspirin is the recommended antithrombotic …
[HTML][HTML] Baseline factors associated with response to ruxolitinib: an independent study on 408 patients with myelofibrosis
F Palandri, GA Palumbo, M Bonifacio, M Tiribelli… - Oncotarget, 2017 - ncbi.nlm.nih.gov
In patients with Myelofibrosis (MF) treated with ruxolitinib (RUX), the response is
unpredictable at therapy start. We retrospectively evaluated the impact of clinical/laboratory …
unpredictable at therapy start. We retrospectively evaluated the impact of clinical/laboratory …
Tamoxifen for the treatment of myeloproliferative neoplasms: A Phase II clinical trial and exploratory analysis
Z Fang, G Corbizi Fattori, T McKerrell… - Nature …, 2023 - nature.com
Current therapies for myeloproliferative neoplasms (MPNs) improve symptoms but have
limited effect on tumor size. In preclinical studies, tamoxifen restored normal apoptosis in …
limited effect on tumor size. In preclinical studies, tamoxifen restored normal apoptosis in …
Sex determines the presentation and outcomes in MPN and is related to sex-specific differences in the mutational burden
The factors underlying the variable presentation and clinical course of myeloproliferative
neoplasms (MPNs) remain unclear. The aim of this study was to evaluate the independent …
neoplasms (MPNs) remain unclear. The aim of this study was to evaluate the independent …
Determinants of patient‐reported xerostomia among long‐term oropharyngeal cancer survivors
P Aggarwal, KA Hutcheson, AS Garden, FE Mott, C Lu… - Cancer, 2021 - Wiley Online Library
Background This study was conducted to identify clinicodemographic risk factors for
xerostomia among long‐term oropharyngeal cancer (OPC) survivors. Methods This cross …
xerostomia among long‐term oropharyngeal cancer (OPC) survivors. Methods This cross …
Heterogeneity in myeloproliferative neoplasms: Causes and consequences
J O'Sullivan, AJ Mead - Advances in biological regulation, 2019 - Elsevier
Myeloproliferative neoplasms (MPNs) are haematopoietic stem cell-derived clonal disorders
characterised by proliferation of some or all myeloid lineages, depending on the subtype …
characterised by proliferation of some or all myeloid lineages, depending on the subtype …
Determinants of cancer-related fatigue among cancer patients: a systematic review
Objectives: This systematic review aims to assess and explore various determinants of
cancer-related fatigue. Methods: A systematic search of various determinants of Cancer …
cancer-related fatigue. Methods: A systematic search of various determinants of Cancer …
Polycythemia vera-associated complications: pathogenesis, clinical manifestations, and effects on outcomes
D Cuthbert, BL Stein - Journal of Blood Medicine, 2019 - Taylor & Francis
Polycythemia vera is a Philadelphia-negative chronic myeloproliferative neoplasm,
characterized by erythrocytosis, which is unique, compared to essential thrombocytosis and …
characterized by erythrocytosis, which is unique, compared to essential thrombocytosis and …