Sex differences in neuronal systems function and behaviour: beyond a single diagnosis in autism spectrum disorders
OOF Williams, M Coppolino, ML Perreault - Translational Psychiatry, 2021 - nature.com
Autism spectrum disorder (ASD) is a complex neurodevelopmental disorder that is
associated with functional brain alterations that underlie the expression of behaviour. Males …
associated with functional brain alterations that underlie the expression of behaviour. Males …
Prefrontal interneurons: populations, pathways, and plasticity supporting typical and disordered cognition in rodent models
Prefrontal cortex (PFC) inhibitory microcircuits regulate the gain and timing of pyramidal
neuron firing, coordinate neural ensemble interactions, and gate local and long-range …
neuron firing, coordinate neural ensemble interactions, and gate local and long-range …
Top-down control of hippocampal signal-to-noise by prefrontal long-range inhibition
Prefrontal cortex (PFC) is postulated to exert" top-down control" on information processing
throughout the brain to promote specific behaviors. However, pathways mediating top-down …
throughout the brain to promote specific behaviors. However, pathways mediating top-down …
The medial septum controls hippocampal supra-theta oscillations
B Király, A Domonkos, M Jelitai… - nature …, 2023 - nature.com
Hippocampal theta oscillations orchestrate faster beta-to-gamma oscillations facilitating the
segmentation of neural representations during navigation and episodic memory. Supra …
segmentation of neural representations during navigation and episodic memory. Supra …
Autism risk gene POGZ promotes chromatin accessibility and expression of clustered synaptic genes
E Markenscoff-Papadimitriou, F Binyameen, S Whalen… - Cell reports, 2021 - cell.com
Deleterious genetic variants in POGZ, which encodes the chromatin regulator Pogo
Transposable Element with ZNF Domain protein, are strongly associated with autism …
Transposable Element with ZNF Domain protein, are strongly associated with autism …
[HTML][HTML] Understanding autism spectrum disorders with animal models: applications, insights, and perspectives
Z Li, YX Zhu, LJ Gu, Y Cheng - Zoological research, 2021 - ncbi.nlm.nih.gov
Autism spectrum disorder (ASD) is typically characterized by common deficits in social skills
and repetitive/stereotyped behaviors. It is widely accepted that genetic and environmental …
and repetitive/stereotyped behaviors. It is widely accepted that genetic and environmental …
Activity of ventral hippocampal parvalbumin interneurons during anxiety
E Volitaki, T Forro, K Li, T Nevian, S Ciocchi - Cell reports, 2024 - cell.com
Anxiety plays a key role in guiding behavior in response to potential threats. Anxiety is
mediated by the activation of pyramidal neurons in the ventral hippocampus (vH), whose …
mediated by the activation of pyramidal neurons in the ventral hippocampus (vH), whose …
The role of aberrant neural oscillations in the hippocampal-medial prefrontal cortex circuit in neurodevelopmental and neurological disorders
The hippocampus (HPC) and medial prefrontal cortex (mPFC) have well-established roles in
cognition, emotion, and sensory processing. In recent years, interests have shifted towards …
cognition, emotion, and sensory processing. In recent years, interests have shifted towards …
Neuronal oscillations: early biomarkers of psychiatric disease?
A Günther, IL Hanganu-Opatz - Frontiers in Behavioral Neuroscience, 2022 - frontiersin.org
Our understanding of the environmental and genetic factors contributing to the wide
spectrum of neuropsychiatric disorders has significantly increased in recent years …
spectrum of neuropsychiatric disorders has significantly increased in recent years …
Amygdala-hippocampus somatostatin interneuron beta-synchrony underlies a cross-species biomarker of emotional state
Emotional responses arise from limbic circuits including the hippocampus and amygdala. In
the human brain, beta-frequency communication between these structures correlates with …
the human brain, beta-frequency communication between these structures correlates with …