Automated in vivo enzyme engineering accelerates biocatalyst optimization
E Orsi, L Schada von Borzyskowski, S Noack… - Nature …, 2024 - nature.com
Achieving cost-competitive bio-based processes requires development of stable and
selective biocatalysts. Their realization through in vitro enzyme characterization and …
selective biocatalysts. Their realization through in vitro enzyme characterization and …
A journey with psychedelic mushrooms: From historical relevance to biology, cultivation, medicinal uses, biotechnology, and beyond
Psychedelic mushrooms containing psilocybin and related tryptamines have long been used
for ethnomycological purposes, but emerging evidence points to the potential therapeutic …
for ethnomycological purposes, but emerging evidence points to the potential therapeutic …
Engineering low-salt growth Halomonas Bluephagenesis for cost-effective bioproduction combined with adaptive evolution
L Zhang, Y Lin, X Yi, W Huang, Q Hu, Z Zhang… - Metabolic …, 2023 - Elsevier
Halophilic Halomonas bluephagenesis has been engineered to produce various added-
value bio-compounds with reduced costs. However, the salt-stress regulatory mechanism …
value bio-compounds with reduced costs. However, the salt-stress regulatory mechanism …
Evaluating the Performance of Automated Machine Learning (AutoML) Tools for Heart Disease Diagnosis and Prediction
LM Paladino, A Hughes, A Perera, O Topsakal… - AI, 2023 - mdpi.com
Globally, over 17 million people annually die from cardiovascular diseases, with heart
disease being the leading cause of mortality in the United States. The ever-increasing …
disease being the leading cause of mortality in the United States. The ever-increasing …
DuBA. flow─ A Low-Cost, Long-Read Amplicon Sequencing Workflow for the Validation of Synthetic DNA Constructs
AA Ramírez Rojas, CK Brinkmann… - ACS Synthetic …, 2024 - ACS Publications
Modern biological science, especially synthetic biology, relies heavily on the construction of
DNA elements, often in the form of plasmids. Plasmids are used for a variety of applications …
DNA elements, often in the form of plasmids. Plasmids are used for a variety of applications …
The pAblo· pCasso self-curing vector toolset for unconstrained cytidine and adenine base-editing in Gram-negative bacteria
E Kozaeva, ZS Nielsen… - Nucleic Acids …, 2024 - academic.oup.com
A synthetic biology toolkit, exploiting clustered regularly interspaced short palindromic
repeats (CRISPR) and modified CRISPR-associated protein (Cas) base-editors, was …
repeats (CRISPR) and modified CRISPR-associated protein (Cas) base-editors, was …
Expanding the toolbox of probiotic Escherichia coli Nissle 1917 for synthetic biology
Abstract Escherichia coli Nissle 1917 (EcN) is a probiotic microbe that has the potential to be
developed as a promising chassis for synthetic biology applications. However, the molecular …
developed as a promising chassis for synthetic biology applications. However, the molecular …
大肠杆菌对木质纤维素水解液抑制物的胁迫耐受性
唐瑞琪， 赵心清， 朱笃， 汪涯 - 生物技术通报, 2023 - biotech.aiijournal.com
木质纤维素类生物质是前景广阔的化石原料替代品, 其生物炼制可生产生物能源,
生物基化学品和生物材料等多种产品, 可降低碳排放, 有助于实现“双碳” 目标 …
生物基化学品和生物材料等多种产品, 可降低碳排放, 有助于实现“双碳” 目标 …
From Rags to Riches: Exploiting the Calvin‐Benson‐Bassham Cycle for Biomanufacturing
Industrial chemical production largely relies on fossil fuels, resulting in the unavoidable
release of carbon dioxide (CO2) into the atmosphere. The concept of a circular carbon …
release of carbon dioxide (CO2) into the atmosphere. The concept of a circular carbon …
高通量平行发酵技术的发展与应用
白仲虎， 任和， 聂简琪， 孙杨 - 合成生物学, 2023 - synbioj.cip.com.cn
21 世纪初, 为解决生物医药过程工程研究所面临的微生物和哺乳动物细胞培养的实验通量,
研发效率与成本方面的问题, 更重要的是质量源于设计(QbD) 导向的生物过程工程实验设计 …
研发效率与成本方面的问题, 更重要的是质量源于设计(QbD) 导向的生物过程工程实验设计 …