Microarray analysis of acute and delayed gene expression profile in rats after focal ischemic brain injury and reperfusion

XCM Lu, AJ Williams, C Yao, R Berti… - Journal of …, 2004 - Wiley Online Library
Temporal changes in gene expression were measured using DNA microarrays after 30‐min
or 2‐hr transient middle cerebral artery occlusion (MCAo) in rats. Total RNA was extracted …

Penetrating ballistic-like brain injury in the rat: differential time courses of hemorrhage, cell death, inflammation, and remote degeneration

AJ Williams, JA Hartings, XCM Lu, ML Rolli… - Journal of …, 2006 - liebertpub.com
Acute and delayed cerebral injury was assessed in a recently developed rat model of a
penetrating ballistic-like brain injury (PBBI). A unilateral right frontal PBBI trajectory was …

EEG patterns and epileptic seizures in acute phase stroke

O Mecarelli, S Pro, F Randi, S Dispenza… - Cerebrovascular …, 2011 - karger.com
Background: The rate of early post-stroke epileptic seizures ranges from 2 to 33%. This wide
range is likely due to differences in study design, patient selection and type of …

Quantitative and qualitative EEG as a prediction tool for outcome and complications in acute stroke patients

JI Doerrfuss, T Kilic, M Ahmadi… - Clinical EEG and …, 2020 - journals.sagepub.com
Currently, the relevance of EEG measurements in acute stroke patients is considered low in
clinical practice. However, recent studies on the predictive value of EEG measurements after …

Prospects of modeling poststroke epileptogenesis

DS Reddy, A Bhimani, R Kuruba… - Journal of …, 2017 - Wiley Online Library
This Review describes the current status of poststroke epilepsy (PSE) with an emphasis on
poststroke epileptogenesis modeling for testing new therapeutic agents. Stroke is a leading …

Imaging reveals the focal area of spreading depolarizations and a variety of hemodynamic responses in a rat microembolic stroke model

Z Bere, TP Obrenovitch, G Kozák… - Journal of Cerebral …, 2014 - journals.sagepub.com
Spreading depolarizations (SDs) occur in stroke, but the spatial association between SDs
and the corresponding hemodynamic changes is incompletely understood. We applied …

Acute ischemic stroke treatment and the occurrence of seizures

J De Reuck, G Van Maele - Clinical neurology and neurosurgery, 2010 - Elsevier
BACKGROUND AND OBJECTIVES: Early intravenous treatment with recombinant tissue
plasminogen activator (rt-PA) improves the outcome of patients with an acute ischemic …

Seizures and CNS hemorrhage: spontaneous intracerebral and aneurysmal subarachnoid hemorrhage

E Gilmore, HA Choi, LJ Hirsch, J Claassen - The neurologist, 2010 - journals.lww.com
Background: Convulsive and nonconvulsive seizures frequently complicate acute brain
injury particularly central nervous system hemorrhages and both have been associated with …

Pathological changes of brain oscillations following ischemic stroke

Y Sato, O Schmitt, Z Ip, G Rabiller… - Journal of Cerebral …, 2022 - journals.sagepub.com
Brain oscillations recorded in the extracellular space are among the most important aspects
of neurophysiology data reflecting the activity and function of neurons in a population or a …

How I treat patients with EEG patterns on the ictal–interictal continuum in the neuro ICU

J Claassen - Neurocritical care, 2009 - Springer
Refractory status epilepticus (RSE) is associated with a high risk of poor outcome and
treated by most neurointensivists with continuous intravenous antiepileptic medications (cIV …