Neuroprotection assessment by topographic electroencephalographic analysis: effects of a sodium channel blocker to reduce polymorphic delta activity following …

AJ Williams, XCM Lu, JA Hartings… - Fundamental & clinical …, 2003 - Wiley Online Library
The spatiotemporal electroencephalogram (EEG) pathology associated with brain injury was
studied using high‐resolution, 10‐electrode cortical EEG mapping in a rat model of middle …

Contributions of the hippocampal CA3 circuitry to acute seizures and hyperexcitability responses in mouse models of brain ischemia

H Song, SM Mylvaganam, J Wang… - Frontiers in Cellular …, 2018 - frontiersin.org
The hippocampal circuitry is widely recognized as susceptible to ischemic injury and seizure
generation. However, hippocampal contribution to acute non-convulsive seizures (NCS) in …

Intrahippocampal Injection of Endothelin‐1: A New Model of Ischemia‐induced Seizures in Immature Rats

G Tsenov, A Mátéffyová, P Mareš, J Otáhal… - …, 2007 - Wiley Online Library
The goal of this study was to develop a new model of ischemia‐induced seizures in
immature rats using injection of vasoconstrictor Endothelin‐1 (ET‐1) into the brain. ET‐1 (10 …

Dual therapeutic effects of C-10068, a dextromethorphan derivative, against post-traumatic nonconvulsive seizures and neuroinflammation in a rat model of …

XCM Lu, DA Shear, PB Graham, GW Bridson… - Journal of …, 2015 - liebertpub.com
Post-traumatic seizures can exacerbate injurious outcomes of severe brain trauma, yet
effective treatments are limited owing to the complexity of the pathology underlying the …

Acute symptomatic seizures following intracerebral hemorrhage in the rat collagenase model

C Germonpré, S Proesmans, C Bouckaert, L Stevens… - Epilepsy Research, 2020 - Elsevier
Background and purpose Intracerebral hemorrhage (ICH) is a known risk factor for the
development of seizures, but little is known about the pathophysiology of seizures in the …

Animal modeling of poststroke seizures and epilepsy: 5-year update

KM Kelly - Epilepsy currents, 2007 - journals.sagepub.com
Poststroke seizures and epilepsy have been described in numerous clinical and
epidemiological studies over many years. In contrast, the pathophysiological events …

Epileptiform electroencephalogram discharges increase seizure recurrence risk in patients with acute symptomatic seizure due to a structural brain lesion

L Grau-López, B Flores-Pina, M Jiménez… - … : European Journal of …, 2024 - Elsevier
Objective The risk factors for seizure recurrence after acute symptomatic seizure due to a
structural brain lesion are not well established. The aim of this study was to analyze possible …

Poststroke epilepsy following transient unilateral middle cerebral and common carotid artery occlusion in young adult and aged F344 rats

KM Kelly, PI Jukkola, G Yin, ER Miller, EA Kharlamov… - Epilepsy research, 2018 - Elsevier
The mechanisms of injured brain that establish poststroke seizures and epilepsy are not well
understood, largely because animal modeling has had limited development. The main …

High-frequency cortical activity associated with postischemic epileptiform discharges in an in vivo rat focal stroke model

LR Srejic, TA Valiante, MM Aarts… - Journal of Neurosurgery, 2013 - thejns.org
Object The postischemic brain has greater susceptibility to epileptogenic activity than
physiologically healthy tissue. Epileptiform discharges are thought to exacerbate …

[引用][C] 超早期脑梗死患者脑电图改变的研究

李光雷, 李玉荣, 王秀艳, 臧贺川 - 临床神经电生理学杂志, 2007