Modeling poststroke epilepsy and preclinical development of drugs for poststroke epilepsy

A Leo, C De Caro, V Nesci, M Tallarico, G De Sarro… - Epilepsy & Behavior, 2020 - Elsevier
Stroke is a severe clinical issue for global public health, representing the third leading cause
of death and a major cause of disability in developed countries. Progresses in the …

Neuroprotective effects of focal brain cooling on photochemically-induced cerebral infarction in rats: analysis from a neurophysiological perspective

Y He, M Fujii, T Inoue, S Nomura, Y Maruta, F Oka… - Brain research, 2013 - Elsevier
Although systemic hypothermia provides favorable outcomes in stroke patients, it has only
been adopted in a limited number of patients because of fatal complications. To resolve …

Use of materials for treatment of central nervous system lesions

M Dezawa, K Mori - US Patent 8,092,792, 2012 - Google Patents
US8092792B2 - Use of materials for treatment of central nervous system lesions - Google
Patents US8092792B2 - Use of materials for treatment of central nervous system lesions …

Dynamic analysis of epileptic seizures caused by energy failure after ischemic stroke

Y Yu, Z Yuan, J Li, Y Wu - Chaos, Solitons & Fractals, 2023 - Elsevier
Energy is essential for neuronal electrical activity. An inadequate energy supply affects ion
homeostasis and even induces epileptic seizures. Ischemic stroke is an important cause of …

Magnetic resonance imaging after seizures in patients with an ischemic stroke

J De Reuck, F Vanhee, G Van Maele… - Cerebrovascular …, 2007 - karger.com
Background: Seizures related to ischemic strokes are harmful. Their pathogenesis is not
very well understood. The present study investigates whether diffusion-weighted imaging …

Preclinical examination of early‐onset thalamic‐cortical seizures after hemispheric stroke

P García‐Peña, M Ramos, JM López… - …, 2023 - Wiley Online Library
Objective Ischemic stroke is one of the main causes of death and disability worldwide and
currently has limited treatment options. Electroencephalography (EEG) signals are …

Continuous electroencephalogram monitoring in critically ill patients

N Jette, LJ Hirsch - Current Neurology and Neuroscience Reports, 2005 - Springer
The past few years have witnessed remarkable advances in continuous EEG monitoring
(cEEG). The indications and applications for cEEG are broadening, including detection of …

Penicillin-induced epileptiform activity elevates focal brain temperature in anesthetized rats

T Tokiwa, T Inoue, M Fujii, S Ishizuka, S Aou… - Neuroscience …, 2013 - Elsevier
To elucidate a relationship between changes in focal brain temperature and severity of
abnormal brain activity, epileptiform discharges and behavioral seizures were induced by …

Delayed transient worsening of neurological deficits after ischaemic stroke

J De Reuck, L De Groote, G Van Maele - Cerebrovascular Diseases, 2006 - karger.com
Background: Although the causes of stroke recurrence are well known, no particular study
deals with the specific issue of late-onset transient worsening of the neurological deficit …

Reduced expression of IA channels is associated with postischemic seizures in hyperglycemic rats

Z Lei, H Zhang, Y Liang, Q Cui, Z Xu… - Journal of …, 2014 - Wiley Online Library
Poststroke seizures are considered to be the major cause of epilepsy in the elderly. The
mechanisms of poststroke seizures remain unclear. A history of diabetes mellitus has been …