Increase in heme oxygenase-1 levels ameliorates renovascular hypertension Background
The heme oxygenase system (HO-1 and HO-2) catalyzes the conversion of heme to free …

Almost a hundred years have passed since obstruction of the renal artery has been
recognized to raise blood pressure. By now chronic renovascular disease (RVD) due to …

Percutaneous transluminal renal stenting (PTRS) does not consistently improve renal
function in patients with atherosclerotic renovascular disease, but the mechanisms …

Methods Renal hemodynamics, function, and endothelial function were quantified in vivo in
pigs after 12 weeks of combined hypercholesterolemia+ renal artery stenosis without (n= 8) …

Higher uric acid levels are associated with an increased risk for developing hypertension.
Higher intake of fructose increases plasma uric acid levels and higher intake of vitamin C …

The major causes of CKD and ESRD are diabetes mellitus and hypertension, which lead to
progressive microvascular damage and loss and set the stage for evolving renal injury. 27 …

Background Renovascular hypertension (RVH) is characterized by chronic inflammation of
the stenotic kidney and progressive renal dysfunction. Neutrophil gelatinase-associated …

Reactive oxygen species are mostly viewed to cause oxidative damage to various cells and
induce organ dysfunction after ischemia‐reperfusion injury. However, they are also …

Reactive oxygen species (ROS) can modulate renal hemodynamics and function both
directly, by leading to vasoconstriction, and indirectly, by inducing renal inflammation and …

Experimental hypercholesterolemia (HC) may lead to microvascular neovascularization, but
the underlying pathogenic mechanism remains unclear. We tested the hypothesis that HC …