FGFR families: biological functions and therapeutic interventions in tumors

Q Liu, J Huang, W Yan, Z Liu, S Liu, W Fang - MedComm, 2023 - Wiley Online Library
There are five fibroblast growth factor receptors (FGFRs), namely, FGFR1–FGFR5. When
FGFR binds to its ligand, namely, fibroblast growth factor (FGF), it dimerizes and …

Role of basic fibroblast growth factor in cancer: biological activity, targeted therapies, and prognostic value

A Ardizzone, V Bova, G Casili, A Repici, M Lanza… - Cells, 2023 - mdpi.com
Cancer is the leading cause of death worldwide; thus, it is necessary to find successful
strategies. Several growth factors, such as vascular endothelial growth factor (VEGF), basic …

Identification and validation of miRNA-TF-mRNA regulatory networks in uterine fibroids

X Peng, Y Mo, J Liu, H Liu, S Wang - Frontiers in Bioengineering and …, 2022 - frontiersin.org
Uterine fibroids (UF) are the most common benign gynecologic tumors and lead to heavy
menstrual bleeding, severe anemia, abdominal pain, and infertility, which seriously harm a …