Immunological causes of obsessive-compulsive disorder: is it time for the concept of an “autoimmune OCD” subtype?
D Endres, TA Pollak, K Bechter, D Denzel… - Translational …, 2022 - nature.com
Obsessive-compulsive disorder (OCD) is a highly disabling mental illness that can be
divided into frequent primary and rarer organic secondary forms. Its association with …
divided into frequent primary and rarer organic secondary forms. Its association with …
Microbial reprogramming in obsessive–compulsive disorders: a review of gut–brain communication and emerging evidence
G Bendriss, R MacDonald, C McVeigh - International Journal of …, 2023 - mdpi.com
Obsessive–compulsive disorder (OCD) is a debilitating mental health disorder characterized
by intrusive thoughts (obsessions) and repetitive behaviors (compulsions). Dysbiosis, an …
by intrusive thoughts (obsessions) and repetitive behaviors (compulsions). Dysbiosis, an …
Regulation of oxytocin receptor gene expression in obsessive–compulsive disorder: a possible role for the microbiota-host epigenetic axis
Background Obsessive–compulsive disorder (OCD) is a prevalent and severe clinical
condition. Robust evidence suggests a gene-environment interplay in its etiopathogenesis …
condition. Robust evidence suggests a gene-environment interplay in its etiopathogenesis …
Anxiolytic effects of chronic intranasal oxytocin on neural responses to threat are dose-frequency dependent
Introduction: Anxiety disorders are prevalent mental conditions characterized by
exaggerated anxious arousal and threat reactivity. Animal and human studies suggest an …
exaggerated anxious arousal and threat reactivity. Animal and human studies suggest an …
Mild internet use is associated with epigenetic alterations of key neurotransmission genes in salivary DNA of young university students
The potentially problematic use of the Internet is a growing concern worldwide, which
causes and consequences are not completely understood yet. The neurobiology of Internet …
causes and consequences are not completely understood yet. The neurobiology of Internet …
Hypermethylation of the oxytocin receptor gene (OXTR) in obsessive-compulsive disorder: Further evidence for a biomarker of disease and treatment response
Obsessive-compulsive disorder (OCD) has recently been linked to increased methylation
levels in the oxytocin receptor (OXTR) gene, and OXTR hypermethylation has predicted a …
levels in the oxytocin receptor (OXTR) gene, and OXTR hypermethylation has predicted a …
Serotonin transporter gene promoter hypomethylation as a predictor of antidepressant treatment response in major depression: a replication study
MA Schiele, P Zwanzger, K Schwarte… - International Journal …, 2021 - academic.oup.com
Background The serotonin transporter gene (SLC6A4; 5-HTT; SERT) is considered a prime
candidate in pharmacogenetic research in major depressive disorder (MDD). Besides …
candidate in pharmacogenetic research in major depressive disorder (MDD). Besides …
Epigenome-wide DNA methylation in obsessive-compulsive disorder
MA Schiele, J Lipovsek, P Schlosser… - Translational …, 2022 - nature.com
In adult patients with obsessive-compulsive disorder (OCD), altered DNA methylation has
been discerned in several candidate genes, while DNA methylation on an epigenome-wide …
been discerned in several candidate genes, while DNA methylation on an epigenome-wide …
An epigenetic rheostat of experience: DNA methylation of OXTR as a mechanism of early life allostasis
Oxytocin is a neuropeptide hormone which is involved in regulation of social behavior,
stress response, muscle contraction, and metabolism. Oxytocin signaling is dependent on its …
stress response, muscle contraction, and metabolism. Oxytocin signaling is dependent on its …
Autoantibodies in patients with obsessive-compulsive disorder: a systematic review
Obsessive-compulsive disorder (OCD) is a frequent and debilitating mental illness. Although
efficacious treatment options are available, treatment resistance rates are high. Emerging …
efficacious treatment options are available, treatment resistance rates are high. Emerging …