[HTML][HTML] Pathogenic mechanisms of post-acute sequelae of SARS-CoV-2 infection (PASC)
ZA Sherif, CR Gomez, TJ Connors, TJ Henrich… - Elife, 2023 - elifesciences.org
COVID-19, with persistent and new onset of symptoms such as fatigue, post-exertional
malaise, and cognitive dysfunction that last for months and impact everyday functioning, is …
malaise, and cognitive dysfunction that last for months and impact everyday functioning, is …
[HTML][HTML] Immune response in COVID-19: addressing a pharmacological challenge by targeting pathways triggered by SARS-CoV-2
To date, no vaccines or effective drugs have been approved to prevent or treat COVID-19
and the current standard care relies on supportive treatments. Therefore, based on the fast …
and the current standard care relies on supportive treatments. Therefore, based on the fast …
[HTML][HTML] A targetable LIFR− NF-κB− LCN2 axis controls liver tumorigenesis and vulnerability to ferroptosis
The growing knowledge of ferroptosis has suggested the role and therapeutic potential of
ferroptosis in cancer, but has not been translated into effective therapy. Liver cancer …
ferroptosis in cancer, but has not been translated into effective therapy. Liver cancer …
[HTML][HTML] Quercetin prevents LPS-induced oxidative stress and inflammation by modulating NOX2/ROS/NF-kB in lung epithelial cells
OJ Sul, SW Ra - Molecules, 2021 - mdpi.com
Oxidative stress caused by the production of reactive oxygen species (ROS) plays a major
role in inflammatory processes. We hypothesized that modulation of ROS via quercetin may …
role in inflammatory processes. We hypothesized that modulation of ROS via quercetin may …
[HTML][HTML] The role and therapeutic potential of NF-kappa-B pathway in severe COVID-19 patients
A Hariharan, AR Hakeem, S Radhakrishnan… - …, 2021 - Springer
Abstract Coronavirus disease 2019 (COVID-19) pandemic has affected health care systems
worldwide. Severe presentations of COVID-19 such as severe pneumonia and acute …
worldwide. Severe presentations of COVID-19 such as severe pneumonia and acute …
[HTML][HTML] Targeting TNF-α for COVID-19: recent advanced and controversies
Y Guo, K Hu, Y Li, C Lu, K Ling, C Cai… - Frontiers in public …, 2022 - frontiersin.org
Recent advances in the pathophysiologic understanding of coronavirus disease 2019
(COVID-19) suggests that cytokine release syndrome (CRS) has an association with the …
(COVID-19) suggests that cytokine release syndrome (CRS) has an association with the …
[HTML][HTML] The role of curcumin in aging and senescence: Molecular mechanisms
A Zia, T Farkhondeh, AM Pourbagher-Shahri… - Biomedicine & …, 2021 - Elsevier
Healthy aging and human longevity are intricate phenotypes affected by environmental
factors such as physical exercise, diet, health habits, and psychosocial situations as well as …
factors such as physical exercise, diet, health habits, and psychosocial situations as well as …
[HTML][HTML] Obesity, inflammation, toll-like receptor 4 and fatty acids
Obesity leads to an inflammatory condition that is directly involved in the etiology of
cardiovascular diseases, type 2 diabetes mellitus, and certain types of cancer. The classic …
cardiovascular diseases, type 2 diabetes mellitus, and certain types of cancer. The classic …
[HTML][HTML] Chronic inflammation in chronic kidney disease progression: role of Nrf2
Despite recent advances in the management of chronic kidney disease (CKD), morbidity
and mortality rates in these patients remain high. While pressure-mediated injury is a well …
and mortality rates in these patients remain high. While pressure-mediated injury is a well …
[HTML][HTML] Molecular pathways involved in COVID-19 and potential pathway-based therapeutic targets
M Farahani, Z Niknam, LM Amirabad… - Biomedicine & …, 2022 - Elsevier
Deciphering the molecular downstream consequences of severe acute respiratory
syndrome coronavirus (SARS-CoV)− 2 infection is important for a greater understanding of …
syndrome coronavirus (SARS-CoV)− 2 infection is important for a greater understanding of …