[HTML][HTML] Epithelial mesenchymal transition and tumor budding in aggressive colorectal cancer: tumor budding as oncotarget
I Zlobec, A Lugli - Oncotarget, 2010 - ncbi.nlm.nih.gov
Epithelial mesenchymal transition (EMT) is proposed as a critical mechanism for the
acquisition of malignant phenotypes by epithelial cells. In colorectal cancer, tumor cells …
acquisition of malignant phenotypes by epithelial cells. In colorectal cancer, tumor cells …
Cancer immunology—analysis of host and tumor factors for personalized medicine
S Ogino, J Galon, CS Fuchs, G Dranoff - Nature reviews Clinical …, 2011 - nature.com
Immune cells in the tumor microenvironment have an important role in regulating tumor
progression. Therefore, stimulating immune reactions to tumors can be an attractive …
progression. Therefore, stimulating immune reactions to tumors can be an attractive …
Artificial intelligence for histology-based detection of microsatellite instability and prediction of response to immunotherapy in colorectal cancer
LA Hildebrand, CJ Pierce, M Dennis, M Paracha… - Cancers, 2021 - mdpi.com
Simple Summary Defects in a DNA repair pathway called mismatch repair (MMR) can lead
to cancer, including colorectal cancer (CRC). The detection of mismatch repair deficiency …
to cancer, including colorectal cancer (CRC). The detection of mismatch repair deficiency …
Stage-dependent alterations of the serum cytokine pattern in colorectal carcinoma
T Kantola, K Klintrup, JP Väyrynen, J Vornanen… - British journal of …, 2012 - nature.com
Background: Inflammation contributes to the pathogenesis of colorectal cancer (CRC), and
cytokine levels are altered during colorectal carcinogenesis. Methods: The serum levels of …
cytokine levels are altered during colorectal carcinogenesis. Methods: The serum levels of …
Pathologic predictors of microsatellite instability in colorectal cancer
JK Greenson, SC Huang, C Herron… - The American journal …, 2009 - journals.lww.com
Identification of microsatellite unstable (MSI-H) colorectal cancers (CRCs) is important not
only for the identification of hereditary nonpolyposis colorectal cancer syndrome but also …
only for the identification of hereditary nonpolyposis colorectal cancer syndrome but also …
The heterogeneous clinical and pathological landscapes of metastatic Braf-mutated colorectal cancer
GN Fanelli, CA Dal Pozzo, I Depetris, M Schirripa… - Cancer Cell …, 2020 - Springer
Colorectal cancer (CRC) is a complex and molecularly heterogeneous disease representing
one of the most frequent causes of cancer-related death worldwide. About 8–15% of CRCs …
one of the most frequent causes of cancer-related death worldwide. About 8–15% of CRCs …
Prognostic and predictive factors in colorectal cancer
I Zlobec, A Lugli - Postgraduate medical journal, 2008 - academic.oup.com
Prognostication of newly diagnosed colorectal cancer (CRC) predominantly relies on stage
as defined by the UICC-TNM and American Joint Committee on Cancer classifications …
as defined by the UICC-TNM and American Joint Committee on Cancer classifications …
CD3+ cells at the invasive margin of deeply invading (pT3–T4) colorectal cancer and risk of post-surgical metastasis: a longitudinal study
L Laghi, P Bianchi, E Miranda, E Balladore… - The lancet …, 2009 - thelancet.com
Background The density of tumour-infiltrating lymphocytes (TIL) has been proposed as an
independent predictor of outcome in patients with colorectal cancer. However, the relative …
independent predictor of outcome in patients with colorectal cancer. However, the relative …
Diagnosis of Lynch syndrome and strategies to distinguish Lynch-related tumors from sporadic MSI/dMMR tumors
J Leclerc, C Vermaut, MP Buisine - Cancers, 2021 - mdpi.com
Simple Summary Microsatellite instability (MSI) is a hallmark of Lynch syndrome (LS)-related
tumors but is not specific, as most of MSI/mismatch repair-deficient (dMMR) tumors are …
tumors but is not specific, as most of MSI/mismatch repair-deficient (dMMR) tumors are …