Management of phaeochromocytoma and paraganglioma in patients with germline SDHB pathogenic variants: an international expert Consensus statement

D Taïeb, S Nölting, ND Perrier, M Fassnacht… - Nature Reviews …, 2024 - nature.com
Adult and paediatric patients with pathogenic variants in the gene encoding succinate
dehydrogenase (SDH) subunit B (SDHB) often have locally aggressive, recurrent or …

Diagnosis and management of pheochromocytomas and paragangliomas: A guide for the clinician

S Sharma, L Fishbein - Endocrine Practice, 2023 - Elsevier
Objective The aim of this review is to provide a practical approach for clinicians regarding
the diagnosis and management of pheochromocytomas and paragangliomas (PPGL) …

Responses to systemic therapy in metastatic pheochromocytoma/paraganglioma: a retrospective multicenter cohort study

A Fischer, S Kloos, H Remde… - European Journal of …, 2023 - academic.oup.com
Objective The therapeutic options for metastatic pheochromocytomas/paragangliomas
(mPPGLs) include chemotherapy with cyclophosphamide/vincristine/dacarbazine (CVD) …

The connection between tricarboxylic acid cycle enzyme mutations and pseudohypoxic signaling in pheochromocytoma and paraganglioma

Y Wang, B Liu, F Li, Y Zhang, X Gao, Y Wang… - Frontiers in …, 2023 - frontiersin.org
Pheochromocytomas and paragangliomas (PPGLs) are rare neuroendocrine tumors
originating from chromaffin cells, holding significant clinical importance due to their capacity …

High incidence of occult familial SDHD cases amongst Czech patients with head and neck paragangliomas

A Guha, A Vicha, T Zelinka, M Kana, Z Musil… - Frontiers in …, 2023 - frontiersin.org
Introduction Head and neck paragangliomas (HNPGLs) are rare neuroendocrine tumors,
which are mostly benign in nature. Amongst all genes, Succinate Dehydrogenase Subunit D …

[HTML][HTML] Improving susceptibility of neuroendocrine tumors to radionuclide therapies: personalized approaches towards complementary treatments

S Richter, C Steenblock, A Fischer, S Lemm… - Theranostics, 2024 - ncbi.nlm.nih.gov
Radionuclide therapies are an important tool for the management of patients with
neuroendocrine neoplasms (NENs). Especially [131 I] MIBG and [177 Lu] Lu-DOTA-TATE …

Multi-disciplinary approach to skull base paragangliomas

SD Curry, A Kocharyan, GP Lekovic - Brain Sciences, 2023 - mdpi.com
The treatment of skull base paragangliomas has moved towards the use of cranial nerve
preservation strategies, using radiation therapy and subtotal resection in instances when …

Surgery for advanced adrenal malignant disease: recommendations based on European Society of Endocrine Surgeons consensus meeting

R Mihai, C De Crea, C Guerin, F Torresan… - British Journal of …, 2024 - academic.oup.com
Methods A working group established by ESES reviewed the current guidelines and
undertook a literature search of the PubMed database focused on several clinical questions …

[HTML][HTML] Genetic diagnosis in acromegaly and gigantism: from research to clinical practice

C Ramírez-Rentería, LC Hernández-Ramírez - Best Practice & Research …, 2024 - Elsevier
It is usually considered that only 5% of all pituitary neuroendocrine tumours are due to
inheritable causes. Since this estimate was reported, however, multiple genetic defects …

Malignant carotid body tumors: What we know, what we do, and what we need to achieve. A systematic review of the literature

C Piazza, D Lancini, M Tomasoni, M Zafereo… - Head & …, 2024 - Wiley Online Library
Malignant carotid body tumors (MCBT) are rare and diagnosed after detection of nodal or
distant metastases. This systematic review (SR) focuses on MCBT initially approached by …