Dose optimisation of PTEN inhibitor, bpV (HOpic), and SCF for the in-vitro activation of sheep primordial follicles

S Adib, MR Valojerdi, M Alikhani - Growth Factors, 2019 - Taylor & Francis
The in-vitro development of primordial follicles is critical for improving mammalian fertility
and wildlife conservation. This study aimed to optimise the effective doses of bpV (HOpic) …

Effects of growth differentiation factor-9 and FSH on in vitro development, viability and mRNA expression in bovine preantral follicles

GL Vasconcelos, MVA Saraiva, JJN Costa… - Reproduction, fertility …, 2013 - CSIRO Publishing
The present study investigated the role of growth differentiation factor (GDF)-9 and FSH,
alone or in combination, on the growth, viability and mRNA expression of FSH receptor …

Protein and messenger RNA expression of interleukin 1 system members in bovine ovarian follicles and effects of interleukin 1β on primordial follicle activation and …

JRS Passos, JJN Costa, EV da Cunha… - Domestic animal …, 2016 - Elsevier
This study aimed to investigate the expression of interleukin 1 (IL-1) system members
(proteins and messenger RNA of ligands and receptors) and its distribution in ovarian …

[HTML][HTML] Ultrastructure of isolated mouse ovarian follicles cultured in vitro

SA Nottola, S Cecconi, S Bianchi, C Motta… - Reproductive Biology …, 2011 - Springer
Background In vitro maturation of ovarian follicles, in combination with cryopreservation,
might be a valuable method for preserving and/or restoring fertility in mammals with …

Alpha lipoic acid supplementation improves ovarian tissue vitrification outcome: an alternative to preserve the ovarian function of Morada Nova Ewe

LVS Ñaupas, DCC Brito, SS de Souza… - Reproductive …, 2021 - Springer
This study evaluated the effect of adding alpha lipoic acid (ALA) to the vitrification solution of
sheep ovarian tissue on 7 days of in vitro culture or 15 days of xenotransplantion. ALA was …

Effects of bone morphogenetic protein 4 (BMP4) supplementation during culture of the sheep ovarian cortex

MJ Bertoldo, N Duffard, J Bernard, C Frapsauce… - Animal reproduction …, 2014 - Elsevier
The aim of the present study was to establish the presence of BMP type I and II receptor
presence in preantral follicles and to investigate the effect of BMP4 supplementation on …

Interactions of indole acetic acid with EGF and FSH in the culture of ovine preantral follicles

ER Andrade, MM Seneda, AA Alfieri, JA de Oliveira… - Theriogenology, 2005 - Elsevier
The mechanisms that regulate the gradual exit of ovarian follicles from the non-growing,
primordial pool are very poorly understood. The objective of this study was to evaluate the …

Regulation of in vitro growth of preantral follicles by growth factors in goats

H Zhou, Y Zhang - Domestic animal endocrinology, 2005 - Elsevier
Goat preantral follicles were cultured to investigate the effects of insulin-like growth factor-I
(IGF-I), epidermal growth factor (EGF) and basic fibroblast growth factor (bFGF) on the in …

Steady-state level of bone morphogenetic protein-15 in goat ovaries and its influence on in vitro development and survival of preantral follicles

JJH Celestino, IB Lima-Verde, JB Bruno… - Molecular and cellular …, 2011 - Elsevier
This study investigates steady-state level of bone morphogenetic protein-15 (BMP-15)
mRNA in caprine follicles, and the effects of BMP-15 on in vitro development of preantral …

Stability of housekeeping genes and expression of locally produced growth factors and hormone receptors in goat preantral follicles

IMA Frota, CCF Leitão, JJN Costa, IR Brito… - Zygote, 2011 - cambridge.org
The aim of the present study was to investigate the stability of six housekeeping genes, and
the relative expression of growth factors (EGF, GDF-9, BMP-15, VEGF, FGF-2, BMP-6, IGF-1 …