[HTML][HTML] Autism spectrum disorder: focus on glutamatergic neurotransmission

M Montanari, G Martella, P Bonsi… - International Journal of …, 2022 - mdpi.com
Disturbances in the glutamatergic system have been increasingly documented in several
neuropsychiatric disorders, including autism spectrum disorder (ASD). Glutamate-centered …

[HTML][HTML] The impact of maternal high-fat diet on offspring neurodevelopment

G Urbonaite, A Knyzeliene, FS Bunn… - Frontiers in …, 2022 - frontiersin.org
A maternal high-fat diet affects offspring neurodevelopment with long-term consequences on
their brain health and behavior. During the past three decades, obesity has rapidly …

[HTML][HTML] Neuroimaging genetics approaches to identify new biomarkers for the early diagnosis of autism spectrum disorder

S Nisar, M Haris - Molecular psychiatry, 2023 - nature.com
Autism-spectrum disorders (ASDs) are developmental disabilities that manifest in early
childhood and are characterized by qualitative abnormalities in social behaviors …

[HTML][HTML] The cortico-striatal circuitry in autism-spectrum disorders: a balancing act

JJ Soghomonian - Frontiers in Cellular Neuroscience, 2024 - frontiersin.org
The basal ganglia are major targets of cortical inputs and, in turn, modulate cortical function
via their projections to the motor and prefrontal cortices. The role of the basal ganglia in …

[HTML][HTML] Application of multimodal MRI in the early diagnosis of autism spectrum disorders: a review

M Wang, D Xu, L Zhang, H Jiang - Diagnostics, 2023 - mdpi.com
Autism spectrum disorder (ASD) is a neurodevelopmental disorder in children. Early
diagnosis and intervention can remodel the neural structure of the brain and improve quality …

Glutamate levels of the right and left anterior cingulate cortex in autistics adults

F Briend, L Barantin, H Cléry, JP Cottier… - Progress in Neuro …, 2023 - Elsevier
Abstract Background The neurobiology of Autism Spectrum Disorder (ASD) is still unknown.
Alteration in glutamate metabolism might translate into an imbalance of the …

The impact of ammonia and microcystin-LR on neurobehavior and glutamate/gamma-aminobutyric acid balance in female zebrafish (Danio rerio): ROS and …

Y He, K Ouyang, H Yang, L Wang, X Wang, D Li… - Science of The Total …, 2024 - Elsevier
Ammonia and microcystin-LR (MC-LR) are both toxins that can be in eutrophic waters during
cyanobacterial blooms. While previous studies have focused on the effects of ammonia …

[HTML][HTML] Dorsolateral prefrontal cortex glutamate/gamma-aminobutyric acid (GABA) alterations in clinical high risk and first-episode schizophrenia: a preliminary 7-T …

A Mayeli, SF Sonnenschein, VE Yushmanov… - International Journal of …, 2022 - mdpi.com
Converging lines of evidence suggest that an imbalance between excitation and inhibition is
present in the dorsolateral prefrontal cortex (DLPFC) of schizophrenia (SCZ). Gamma …

Epigenetic underpinnings of the autistic mind: Histone modifications and prefrontal excitation/inhibition imbalance

YA Fard, EN Sadeghi, Z Pajoohesh… - American Journal of …, 2024 - Wiley Online Library
Autism spectrum disorder (ASD) is complex neurobehavioral condition influenced by several
cellular and molecular mechanisms that are often concerned with synaptogenesis and …

[HTML][HTML] The gut metabolite indole-3-propionic acid activates ERK1 to restore social function and hippocampal inhibitory synaptic transmission in a 16p11. 2 …

J Jiang, D Wang, Y Jiang, X Yang, R Sun, J Chang… - Microbiome, 2024 - Springer
Background Microdeletion of the human chromosomal region 16p11. 2 (16p11. 2+/-) is a
prevalent genetic factor associated with autism spectrum disorder (ASD) and other …