Patient-derived T cells genetically reprogrammed to express CD19-specific chimeric antigen
receptors (CARs) have shown remarkable clinical responses and are commercially …

Immuno-positron emission tomography (immunoPET) is a paradigm-shifting molecular
imaging modality combining the superior targeting specificity of monoclonal antibody (mAb) …

Decreased NAD+ levels have been shown to contribute to metabolic dysfunction during
aging. NAD+ decline can be partially prevented by knockout of the enzyme CD38. However …

The recent, fast development of nanotechnology is reflected in the medical sciences.
Superparamagnetic Iron Oxide Nanoparticles (SPIONs) are an excellent example. Thanks to …

Radiometals possess an exceptional breadth of decay properties and have been applied to
medicine with great success for several decades. The majority of current clinical use …

Immunoassays are antibody-based analytical methods for quantitative/qualitative analysis.
Since the principle of immunoassays is based on specific antigen–antibody reaction, the …

Amplification of epidermal growth factor receptor (EGFR) and its active mutant EGFRvIII
occurs frequently in glioblastoma (GBM). While EGFR and EGFRvIII play critical roles in …

Safety and efficacy constitute the major criteria governing regulatory approval of any new
drug. The best method to maximize safety and efficacy is to deliver a proven therapeutic …

The global sanitary crisis caused by the emergence of the respiratory virus SARS-CoV-2
and the COVID-19 outbreak has revealed the urgent need for rapid, accurate, and affordable …

Biological specimens are intrinsically three dimensional; however, because of the obscuring
effects of light scatter, imaging deep into a tissue volume is problematic. Although efforts to …