Repurposing pantoprazole in combination with systemic therapy in advanced head and neck squamous cell carcinoma: a phase I/II randomized study

V Noronha, V Patil, N Menon, D Kalra, A Singh… - Medical Oncology, 2023 - Springer
Pantoprazole decreases the acidity of the tumor microenvironment by inhibiting proton
pumps on the cancer cell. This possibly leads to increased sensitivity to cytotoxic therapy …

[HTML][HTML] Metronomic therapy using methotrexate and celecoxib: a boon for oral cancer patients during COVID-19 pandemic

M Imaduddin, M Sultania, B Vigneshwaran… - Oral …, 2021 - ncbi.nlm.nih.gov
The COVID-19 pandemic has crippled the healthcare system worldwide, with over 35 million
cases and 1.04 million deaths by the first week of October. India, with a population of over …

Role of metronomic therapy for advanced oral cancers and predictors of response: Multi‐institutional feasibility study

M Sultania, M Imaduddin, S SV Deo, M Kar… - Head & …, 2022 - Wiley Online Library
Background In an era of targeted therapies, patients with cancer in resource‐constraint
countries continue to struggle to find affordable care. Methods The present study is a …

Global inequalities in availability of systemic therapies for cancer care and strategies to address them

M Krishnan, P Agarwal, R Pinninti… - Journal of Surgical …, 2023 - Wiley Online Library
Many Low and middle‐income countries face challenges in delivering chemotherapy
services due to limitations in infrastructure, inadequate healthcare facilities, and a shortage …

[HTML][HTML] Novel regimens of phytopolyphenols and celecoxib enhancing efficacy and selectivity of anticancer effects of chemotherapeutic agents on cultured cancer …

MY Chou, SY Lin-Shiau - Journal of Dental Sciences, 2024 - Elsevier
Background/purpose Explorations of novel regimens enhancing efficacy and selectivity of
chemotherapeutic agents are urgent to solve the problems of cancer therapy. This study …

[HTML][HTML] Aggressive anticancer treatment in the last 2 weeks of life

N Golob, T Oblak, L Čavka, M Kušar, B Šeruga - ESMO open, 2024 - Elsevier
Background There is a concern that terminally ill cancer patients may be aggressively
treated due to the rapidly growing possibilities of anticancer treatment. The aim of this study …

Anaplastic cancer: Our experience

APK Kanteti, J Ghose, VM Patil, AS Tamhankar… - Indian Journal of …, 2022 - Springer
Anaplastic thyroid carcinoma (ATC) is a rare thyroid malignancy with a dire prognosis,
nearly 100% disease specific mortality and a median overall survival less than 6 months. In …

[PDF][PDF] Metronomic Chemotherapy in Oral Cancer: A Review

S Sethuraman, K Ramalingam - Cureus, 2023 - cureus.com
Abstract Treatment of locally advanced oral cancer requires multidisciplinary care, including
surgery, radiotherapy, and chemotherapy, which varies based on the stage of the disease …

[HTML][HTML] The application of salvage surgery improves the quality of life and overall survival of extensively recurrent head and neck cancer after multiple operation plus …

L Zhang, Q Xu, H Liu, B Li, H Wang, C Liu, J Li… - Frontiers in …, 2022 - frontiersin.org
Objectives: The prognosis, choice of reconstruction and the quality of life (QOL) after salvage
surgery (SS) for extensively locoregional recurrent/metastatic head and neck cancer (R/M …